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PectaSol-C shows good results with relapsed cancer

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Prostate Cancer
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reachout
Veteran Member
Joined : May 2009
Posts : 744
Posted 2/8/2018 4:49 AM (GMT -8)
I had never heard of it, but a supplement called PectaSol-C, a modified citrus pectin, is showing good results in extending doubling time for those of us whose cancer has returned. It's a small study and the rrsults are preliminary, but this is from the paper:

A stabilization or improvement (increase) of PSA doubling time was noted in 79% (n = 27) of pts. Disease progression at 6 mos was noted in 38% (n = 13: PSA only 29%, n = 10; PSA and scans 9%, n = 3). 

ascopubs.org/doi/abs/10.1200/JCO.2017.35.15_suppl.e16588

Has anyone tried this?
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Cigafred
Regular Member
Joined : Aug 2014
Posts : 193
Posted 2/8/2018 5:44 AM (GMT -8)
Have used modified citrus pectin for maybe six months, no idea if helping or not. It is said somewhere that the maintenance dose is 5 gram/day.
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PeterDisAbelard.
Forum Moderator
Joined : Jul 2012
Posts : 6409
Posted 2/8/2018 5:51 AM (GMT -8)
I seem to recall some discussion of this stuff here a few years ago. At that time there were a few studies that were encouraging, especially if you happened to be a mouse. I am glad to see that human trials are proceeding.

Here's a nicely-written review of some of the research as of ten years ago:

Modified citrus pectin anti-metastatic properties: one bullet, multiple targets

For those of you who like to rush out and try everything new and exciting, or the more cautious types who insist on more mature research but suspect they may be mice, you can buy the stuff from Amazon. It's slightly expensive as supplements go but as a cancer treatment it's dirt cheap. At the dose mentioned in reachout's study (roughly 15g a day, taken as 3 5g doses) it costs four or five bucks a day as a bulk powder and about twice that if you prefer it in capsule form.
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reachout
Veteran Member
Joined : May 2009
Posts : 744
Posted 2/8/2018 5:59 AM (GMT -8)
Cigafred do you get it in capsules or powder. From what I read it tastes pretty bad in powder but may be absorbed better. In pill form looks like you have to take 3 to 6 pills three times a day to get 5g per serving. Is that correct?
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Tall Allen
Elite Member
Joined : Jul 2012
Posts : 10645
Posted 2/8/2018 10:57 AM (GMT -8)
That study had no control group so I wouldn't draw any inferences from it. (other supplements make the claim of extending PSADT, but the advantage disappears when a control group is used) But it seems to be a harmless supplement, so I don't see any reason not to take it. Maybe just use more orange marmalade on your toast? I know one prostate oncologist who touts it to her patients.
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reachout
Veteran Member
Joined : May 2009
Posts : 744
Posted 2/8/2018 8:16 PM (GMT -8)
Here's a review article. Apparently this has been looked at for a long time. There's been good results in extending doubling time on mice (with control group), in vitro human cancer cells, and now with a small set of patients. May or may not work but as TA says, it seems harmless -- except to the wallet.

/prostate.net/articles/pectasol-c-modified-citrus-pectin-for-prostate-cancer
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PDL17
Veteran Member
Joined : Oct 2011
Posts : 686
Posted 2/8/2018 5:56 PM (GMT -8)
I looked into it in 1994 for my dad to treat his prostate cancer. We decided it didn't look that useful. I haven't kept up with the literature on this so I would not take my 1994 opinion of it seriously.

Paul
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Cigafred
Regular Member
Joined : Aug 2014
Posts : 193
Posted 2/9/2018 5:04 AM (GMT -8)
@Reachout. I use the powder, almost tasteless to me (and I can do ok on blind wine-tasting contests). Dissolving it requires a bit of effort, I let it soak for maybe ten minutes, then stir awhile, maybe it isn't necessary for it to be dissolved?
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Wilderness
Regular Member
Joined : Feb 2015
Posts : 393
Posted 2/9/2018 7:42 AM (GMT -8)
Powdsr here too. Couple of teaspoons in dry glass, stir vigorously adding water to half full. Finish with pomegranate.
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reachout
Veteran Member
Joined : May 2009
Posts : 744
Posted 2/9/2018 8:14 AM (GMT -8)
OK I ordered the powder and one of those frothing things to mix it well. Wilderness, I love your psa history, hopefully I can duplicate it.
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Gear
Regular Member
Joined : Oct 2016
Posts : 356
Posted 2/9/2018 8:43 AM (GMT -8)
I have been taking the pills.... when I remember to take them.
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Stephen S
Veteran Member
Joined : Oct 2019
Posts : 582
Posted 6/29/2022 3:09 AM (GMT -8)
So I realize am resurrecting an old thread.

Is anyone using this supplement? Did it make a difference?
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Cigafred
Regular Member
Joined : Aug 2014
Posts : 193
Posted 6/29/2022 4:09 AM (GMT -8)
Replying to Reachout ( a mere 4.5 years later, is that a record?). Sorry, I did not see it before.
I still take modified citrus pectin, most recently Now brand. PectaSol-C has the clinical trial (run by the company) to back it, but I decided any cheaper brand would do as long as it has a similar low molecular weight. I also only buy powder as it is cheaper. As suggested by Nalakrats on a different forum, for this and for IP/IP6, I just toss it into by mouth/throat and wash it down with water--saves time. And I really like the taste of the Now modified citrus pectin.
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Duck2
Regular Member
Joined : Dec 2019
Posts : 429
Posted 6/29/2022 7:45 PM (GMT -8)
Do enough searching and you will find a study that did not indicate any benefit from modified citrus pectin.
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