Brachy boost therapy and RP both extend survival in high risk patients, but brachy boost does more

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Tall Allen
Elite Member


Date Joined Jul 2012
Total Posts : 10645
   Posted 3/8/2018 12:10 PM (GMT -6)   
Two studies published in the last week overlap in that they both tell us that overall survival is no different between bracy boost and surgery. But the enlarged, updated Kishan study shows a clear advantage to brachy boost in terms of prostate cancer-specific survival and metastasis-free survival compared to surgery or EBRT only.

/pcnrv.blogspot.com/2018/03/brachy-boost-therapy-and-surgery-extend.html
Allen - not an MD
•PSA=7.3, prostate volume=55cc, 8/17 cores G6 5-35% involvement
SBRT 9 yr onc. resultsSBRT 7 yr QOL results
•treated 10/2010 at age 57 at UCLA,PSA now: 0.1,no lasting urinary, rectal or sexual SEs
my PC blog

Tall Allen
Elite Member


Date Joined Jul 2012
Total Posts : 10645
   Posted 3/15/2018 7:59 PM (GMT -6)   
A third study came along today, and said exactly the same thing -- that escalated dose radiation (79 Gy vs 70 Gy) does not extend overall 8-year survival any more than lower dose radiation, but does extend progression-free survival, and metastasis-free survival. (Median age at treatment was 71).

/jamanetwork.com/journals/jamaoncology/article-abstract/2675014
Allen - not an MD
•PSA=7.3, prostate volume=55cc, 8/17 cores G6 5-35% involvement
SBRT 9 yr onc. resultsSBRT 7 yr QOL results
•treated 10/2010 at age 57 at UCLA,PSA now: 0.1,no lasting urinary, rectal or sexual SEs
my PC blog

logoslidat
Veteran Member


Date Joined Sep 2009
Total Posts : 6078
   Posted 3/15/2018 8:31 PM (GMT -6)   
And in a true dialetic manner...the scientific method{a true dialetic} will either respond to this with a complete opposing view/...or not...if it does not...the study is not therefore correct...it is just unchallenged for reasons...that may or may not be relevant...either way...their relevance...is not relevant to the truth...be cause...its not the nature of the dialect/scientific method to find the truth...merely to approach it...the denoument is released ...in a chimera of faith...which is never known in its own time...but will...suffice { think suffer}...short time...to short time...till evolution in spirit and flesh...expands the universe at a an exponential rate...just follow the bouncing ball...its not rocket science.... Having said all that...even newtons discoveries...tho wrong...did explain and progress knowledge....providing genuine relief and comfort...to its time...in more simpler words...we take what we can get...willy nilly...and the reflected creativity...from the source{does it really matter its title}provides sustainable hope ...and motivation to keep on keeping on...what else we got to do...
gleason 9 contained stopped psa testing jan 2015 with two consecutive psa's a year apart at 0.15
surgery 10/09 only treatment...eyes wide open...no sand...gonna live til I die...not the reverse forgive my virtues as well as my sins...

JNF
Veteran Member


Date Joined Dec 2010
Total Posts : 3886
   Posted 3/16/2018 4:35 AM (GMT -6)   
Thanks TA, excellent information. Of course this adds to my own confirmation bias regarding treatment methods and justifyingly so. Personally, I was convinced more than seven years ago that brachytherapy and external beam was best for me. The stream of studies and my own experience shows the value.
PSA 59 on 8-26-2010 age 60. Biopsy 9-8-2010 12/12 positive, 20-80% involved, PNI in 3 cores, G 3+3,3+4,and 4+3=G7, T2b.
Eligard and Jalyn started on 10-7-2010. IMRT to prostate and lymph nodes started on 11-8-2010, HDR Brachytherapy December 6 and 13, 2010.
PSA < .1 since February 2011. Located in Cumming Georgia north of Atlanta
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