I'm sorry that your colitis excluded you from the trial, but that other trial sounds promising if it makes it past phase 1. All of these trials have their own inclusion and exclusion criteria, which you can find on clinicaltrials.gov
. I was nearly excluded from the Prostvac trial because my medical records had a reference to eczema from my dermatologist. Dana Farber arranged an urgent appointment with my UMass Medical Center dermatologist (it usually takes months to get an appointment) and she confirmed to DF that the minor winter skin rash on my hands a few years ago was not eczema as it is defined by the trial's guidelines. Even though I dodged that bullet I ended up excluded because of the increase in my doubling time. These trials do have to stay within their defined boundaries, otherwise they could end up with invalid results. From our point of view as patients we are hoping for a new and better treatment, but from the viewpoint of the trial we are volunteer lab rats.
Your MO may not have brought it up because your PSA doesn't yet fall within the trial's minimum requirement which is "more than.0.8". Even though by the usually accepted guidelines you are in BCR once your PSA has passed 0.2, the trial has a higher minimum. This is probably, in part, because it is hard to establish a reliable doubling time before PSA hits 1.0 or so. Your DT looks like about
a year or so right now, but you can't know that reliably with measurements still in the low tenths. You can see in my signature that my PSA remained undetectible for several years after SRT and even when it reappeared in stayed in the 0.0x range for a couple of years. However it then began increasing quickly. If your PSA should jump to 0.8 or higher while the trial is still recruiting you could call your MO and ask to be considered for the trial.
-2002-PSA 9.4, 5 of 10 cores positive - 30-50%.
-RP 2002. PT3B N0 MX Gleason=7 (3+4), 75% left lobe; small focus rt lobe.
-PSA low of 0.01; slow rise to 0.4 (2009).
-SRT 2010. One lymph node targeted. Casodex 3 months during SRT -PSA 0.00 through Apr 2014;
-0.02 Oct 2014; 0.04 Apr 2016; 0.23 Oct 2016; 0.51 Jan 2017; 0.64 Mar 2017, 0.92 Jun 2017, 1.54 Oct 2017, 2.46 Jan '18, 3.84 Apr '18
Post Edited (Bohemond) : 4/12/2018 8:12:37 AM (GMT-6)