I have a friend who was on the TRANSFORMER trial for about
4 months. He was on the BAT arm, though unfortunately the high-T phase didn't help him. He's been metastatic for a couple of years, and both first and second level hormone therapies have failed for him. So, BAT seemed like an interesting option. He did feel better with a decent testosterone level, while it lasted. It declined during the month after each shot. It's an interesting theory, but not universally helpful it seems.
Symptomatic mets were an exclusion for the trial, which is something to keep in mind before doing a testosterone boost. I've never heard a good explanation of why this happens, but apparently it can cause mets to become very painful almost immediately after the injection. It happens too fast to be a result of sudden growth of the bone lesions.
55@Dx on 4/16/13. PSA 5.2, G9(5+4), PNI+, cT3a by MRI.
IGRT - 44 sessions (79.2 Gy, 50.4 Gy pelvic)
ADT2 - Lupron+Casodex (5/13-3/16)
8/13-5/16 <0.1 (ADT2)
5/16-3/17 recovering from ADT2
3/17-7/18 ~ 0.6 - 0.8 (no TX)
10/18 = 1.0My Story