But is a belief that there are alternatives to expensive, prescript
ion meds that often have severe SEs, based in logic, and science, or in irrational belief?
I have linked to a boatload of studies here over the years, sometimes even the revered RCTs, that show conclusively that this substance or another- or some way of eating- is at least very helpful with one thing or another. Not a replacement for standard meical treatment, but maybe a help with the disease or preventing it. But often some folks respond as though I am presenting an ad for snake oil with no evidence whatsoever, even in the face of an RCT. These RCTs have not been for prostate cancers, but sometimes for other cancers as an OT post, or other illnesses. Sometimes I get an "you have once again confused the PC forum with breast cancer forum" type of response. As though none of us would be interested in these other diseases either we or our love ones might suffer from, or wonder "Gee, I wonder what else this cheap, mostly SE free substance or diet might be good for?".
In fact, I almost did another one a couple of days ago, a study I had stumbled upon, but in the end I didn't because I didn't want to stir up a bunch of negative responses. It had nothing to do with any cancer, but coincidentally the placebo controlled RCT was done by Iranian Urologists(and they have real doctors in Iran). This was a study on using turmeric- the whole spice like you can buy in the grocery store, about
maybe 1/4 teaspoon per meal or something like that- vs kidney damage caused by the inflammation of Lupus. The turmeric was extremely helpful. It decreased proteinuria, hematuria, and systolic blood pressure—the cardinal clinical manifestations in patients suffering from relapsing or refractory (meaning, untreatable) lupus kidney inflammation. There is a prescript
ion drug for this disease, but it cost many thousands per year and has some very serious SEs. There were no significant unwanted SEs noted with the turmeric. So I thought of posting that here under the thought of "Gee, wonder what else it might be good for", but then I hesitated. But this thread inspired me to at least mention it. I mean, there it is, in black and white, from the scientists, not magical thinking: the spice turmeric was very significantly helpful with this urological disease(kidney inflammation), caused by another disease, Lupus. Sounds like at the least it might reduce the required dose and thus SEs of the drug, not to mention cost. What patient would not want to know that? Some symptoms were reduced 73% from baseline. Placebo did zilch.
As in all cases, one wonders about
bias. But it is easy to to see why some medical or pharmacy types might be biased against turmeric or whatever vs their 35K per year drug. But what would be the bias of these Iranian urologists? Perhaps they are hoping to increase sales of dirt cheap turmeric after they corner the market? Probably not.
I take rather an opposite view from some. I can not understand why every one would not want to know if there was any close to harmless substance, dirt cheap, that might help whatever disease is being considered, even if it is likely that it will only help 10%? If it were a dangerous, expensive drug, well sure, you would want a much higher standard of proof before you risked taking it and spent a fortune on it. But some vitamin, herb or food for which no significant harm(at least at recommended doses) has yet been shown, costing me maybe a few $ a month? Call me irrational or easily duped, but I'm going for it.
But I am glad that my niece, diagnosed with stage 4 breast cancer 8 years ago, was put on 10K IU/day of vitamin D. Because if a doctor says it, well can any one here really claim they know more about
these things than a licensed physician? We don't advise people to not follow their cancer doctors advice, do we? And I doubt that this doctor has a belief system that can not be refuted with logic. I bet he has looked at the studies and has come to a logical conclusion about
possible risk vs possible benefit. https://www.sciencedirect.com/science/article/pii/s1051227611000641
A significant decrease in proteinuria was found when comparing pre- (954.2 ± 836.6) and 1, 2, and 3 months supplementation values (448.8 ± 633.5, 235.9 ± 290.1, and 260.9 ± 106.2, respectively) in the trial group. Also, systolic blood pressure and hematuria were found to decrease significantly when pre- and post-turmeric supplementation values were compared in the trial group. However, placebo capsules did not exert any statistically significant effect on measured variables in the control group over 3 months of the study. No adverse effect related to turmeric supplementation was observed during the trial.
Short-term turmeric supplementation can decrease proteinuria, hematuria, and systolic blood pressure in patients suffering from relapsing or refractory lupus nephritis and can be used as an adjuvant safe therapy for such patients.
Makes me wonder what else it MIGHT be good for?
PSA 10.9 ~112013
Bx on 112013 at age ~65yrs, with 5 of 12 pos, G9(5+4), T2B.
RALP with lymph nodes at Vanderbilt 021914. (nodes clear, SV+, G9 down graded to 4+5, 1 focal margin )
only rare pad use after 1 year
PSA <.01 on 6/14 and all until 9/15 = .01, still .01 9/16, .02 on 3/17,6/17,10/17, .06 1/18, .06 4/18, <.05 7/18, .06 10/1
Post Edited (BillyBob@388) : 10/31/2018 11:18:42 PM (GMT-6)