For a real eye -
opener, get all of your pituitary hormone levels charted out before you start Lupron or Eligard or Firmagon or any other luprolide - related chems, then get them checked again while you are on the chems. I did that, and it has given me the rather (more) serious view of those chems that I currently have.
Look - what the doc is focused on is what he/she intends the treatment to do. They want to deprive the PCa of testosterone, which is a hormone, so they call the therapy "hormone therapy". The drugs stop testosterone production in the testes via depriving them of gonadotrophin (a pituitary hormone). This is accomplished by having a chemical constantly present in your blood stream that jams your hypothalamus up completely so it jams up/shuts down your pituitary gland completely. So what?
"The hypothalamus plays a significant role in the endocrine system. It is responsible for maintaining your body’s internal balance, which is known as homeostasis. To do this, the hypothalamus helps stimulate or inhibit many of your body’s key processes, including:
Heart rate and blood pressure
Fluid and electrolyte balance, including thirst
Appetite and body weight
Glandular secretions of the stomach and intestines
Production of substances that influence the pituitary gland to release hormones
The hypothalamus is involved in many functions of the autonomic nervous system, as it receives information from nearly all parts of the nervous system. As such, it is considered the link between the nervous system and the endocrine system. "
"it not only controls the actions of the pituitary but it secretes at least nine hormones to the pituitary's seven."
linkie - poo:
The effects of this on the human body are profound. In some ways it is like hunting sparrows with a 12 gauge pump shotgun. It works, but kinda makes a mess while doing so. Yeah, these chems are the front line defense against the foe at this time and they do work...for a while.
I call it kicking the can down the road though.
67 yo, 2012 PSA=11, 12/12 cores +. DVRP 12/27/12. 36 g gland 35% PCa,EC ext., 2 SV+,+ marg T3bNXMX, G7(4+3). 2 week post-RP PSA=0.2, Firmagon ADT. Cont @ 3 mo, EBRT prostate bed and interior pelvic lymph nodes ~ 80 Gy/40 ses. Last 6 mo. Eligard 10/14. 4/15 T=2.2, PSA<.02. 10/16 T=204, PSA=.08, 2/17 PSA=.13, 3/17 T=307 PSA=.19, 4/17 PSA=.21, 4/18 PSA=.65 6/18 PSA=1.15 8/18 PSA=1.15 11/18 PSA=1.58