Looking at your stats, it seems unlikely to me that the increase, if real, results from cancer, especially metastatic. You're a Gleason 6, confirmed by Hopkins, and an MRI shows you're unlikely to have EPE, and your PSA was lower before treatment than your latest. For this increase to be cancer related seems highly unlikely. In fact, if you had not been treated at all it's unlikely your PSA would have increased as much.
It could be a benign bounce (common occurrence), but it's a bit on the high side for a bounce but possible (mine doubled). I don't see that you have a history of prostatitis, but that would be my bet, assuming it's not an error, unless you had sex before the PSA or a long bike ride. Could be prostatitis and a bounce at the same time.
I'd call my RO and have this discussion and not drive myself crazy waiting until mid January.
Age 69 DX 06/14 1 of 24 cores positive, 5% involved, (3+4), psa 6.2
2nd opinion from JH (3+3)
3rd opinion from UFPTI (3+4)
mpMRI Duke: 50% chance of SV spread
SV fusion biopsy Duke 10/2014 negative
proton at UFPTI 11/14-01/15
Post Edited (hrpufnstuf) : 11/24/2018 5:34:54 AM (GMT-7)