I am on intermittent HT. I was diagnosed over 6 years ago with gl9/4 and had a DaVinci, IMRT and Lupron/Casodex. I was on the HT for 18 months thru May 2014. So I have been on an HT holiday for over 4.5 years during which time my psa has increased from <.1 to .6. The doubling time seems to be less than 1 year. My MO is just carefully watching me and hopes I get at least another year out of this first holiday. Bottom Line: Intermittent has been very good for me so far.
That's kind of an unusual concept of an intermittent HT "holiday" . Your HT was part of your initial treatment plan, and your numbers are great. A durable remission is our goal, after all. I wouldn't apply your situation to someone asking about intermittent HT for a recurrent case. Of course, as a T4, maybe you look at it differently. Still, you've only had primary therapy and are getting excellent results to date. Intermittent HT is the term normally associated with a recurrence, where one goes on HT as the first salvage therapy. That is then cycled off and on as has been discussed.
G9 cases in some studies are called out as a category that is generally not recommended for intermittent HT due to its aggressiveness.
Yours would be declared recurrent if the PSA hits 2 or so, but some docs would not be comfortable waiting even that long.
[Edit: I'm sorry, I somehow completely overlooked the "DaVinci" comment in your post. My bad. My response was all wrong, since I was thinking you'd only had radiation and HT. Rats. Recurrence for post surgery is when it reaches 0.2, but you probably know that. I assume that's why your surgery was followed up by RT and HT. So I understand your statement about
the HT holiday. Sorry for anyone that error misled, too. Goodness. I really missed that one. I'll just show myself out....]
Post Edited (Redwing57) : 12/19/2018 7:25:10 PM (GMT-7)