Finally PSA <0.05 after RP, RT, ADT + Zytiga.

Guess I'll take this as a small win in this battle that started just a few months ago.

Just need to watch the Zytiga side effects as my liver enzymes (ALT) doubled over the past 6 weeks. Still, it appears the upper threshold for stopping is if you hit 5x the original baseline.

Now I just need to get through 20 EBRT treatments and another 14-22 months of ADT....and then hope T comes back and PSA remains undetectable til the day I die in my sleep from something else. Wow...spelling that out made me realize this journey has a long way to go.

Anyway, thanks to all for the participation in this forum. Such a helpful resource and friendly crowd.
Time to go check the waves....

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52 year old. DX 6/18. PSA 10.8. GS 4+3.
8/18 - RALP at Stanford. Neg margins, 15 neg nodes, neg bone, CT, PSMA/PET scan. PT2c.
9/18 PSA 4.0!
11/18 - PSA 4.5 - Axumin and 2nd review of PSMA id 2 pelvic lymph nodes. Started Lupron.
12/18 - PSA 0.37. Started Zytiga. Starting EBRT (35 fractions, 70 & 50 gr.) at Stanford.
1/19 - PSA <0.05 ng/mL.

As Andrew said, the EBRT is a marathon, but you'll get through it, its not too difficult.

Congrats on the undetectable, thats a big win, not a small one.

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I am not a doctor, just another guy without a prostate
Dx Age 64 Nov 2014, PSA 4.3
BX 3 of 12 cores positive original pathology G6
RALP with Dr Ash Tewari Jan 6, 2015
Post surgical pathology G7 (3+4), - ECE, - Margins, -LN, -SV (+ frozen section apex converted to negative)
PSA @ 6 weeks 2/15, .<02, remained <0.02 until January 2017, .02, repeat Feb 2017, still .02. May 2017-.033, August 2017- .033 November .046, March 2018 .060. June 2018 .068, July 2018 - .082, August 2018, .078, August 2018 - .08 Start ADT. Sept 2018 Start SRT
Sept 2018 thru November 2018 – T = 4, PSA = <.05
Decipher test, low risk, .37 score
My story.... tinyurl.com/qgyu3xq

My liver enzymes just missed the 5x mark, Stopped Zytiga for 7 weeks to get back to normal. Started back at 1/2 dose and now on 3/4 dose. ALT & AST are on the rise again. More blood work in store. My phleb loves me. She's my wife.

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Dx 5/18/17
11/12 cores 2 4+4
RALP 7/27/17; 3 pos nodes
No RT b/c scan show multiple bone mets
Clev Clinic ups to to G9
CClinic MO+my MO say ADT+Zytiga+Pred
psa post op 0.15 to 0.28
lupron 11/17
start zytiga 12/15
psa 12/28 0.03
4/4/18=<0.01
7/3=<0.01
stop Zytiga 7/16 bad liver #'s
9/11/18 restart Zytiga
9/17 down to 1/2 dose
10/5=<0.01
10/30 start 3/4 dose
1/19=<0.01 but liver#'s up again