Oh by the way, does anyone know all the other body organs that produces PSA? I only know of salivary glands.
Don't know about
*all* of them, but below are *some* more...
From this older document:http://clinchem.aaccjnls.org/content/clinchem/41/1/7.full.pdf
"However, as with many stories in biology, the tale of PSA’s specificity is more interesting and complex than was first appreciated. The discovery that PSA could be detected by immunohistochemical methods in female
periurethral glands ended the notion that PSA was absolutely specific to prostate, semen, and gender (13, 14).
Using similar methods, later investigators found that PSA could be detected in apocrine sweat glands, apecrine breast cancers (15), and salivary gland neoplasms (16)-further confirming PSA’s lack of absolute tissue and gender specificity. PSA recently has also been detected in the periurethral and anal glands of men (17, 18). Its presence in the urine of men after cystoprostatectomy (19) indicates that the male urethra is an- other small but measurable tissue source for PSA."
And this document provides more research on the peri-urethral source (you have to page down a few pages in the link to get to the full text):https://www.researchgate.net/publication/47447046_what_are_the_possible_reasons_for_urethral_psa_varieties_after_radical_prostatectomy
Hope this helps.
Jan '08-'11 PSAs 2.2 2.5 2.7 2.6, DREs-
Jan '12: PSA 3.6, DRE+
Jan '12: MRI inconclusive
Feb '12: PCaDx pT2a, 4/12+ (3 @ 3+3, 1 @ 4+3); 3% tot cores; bone scan-
Apr '12: RALP; 3+4=7; pT2c pN0 pMx; 30%; 3mm r lat margin of 3+3=6 so pT2+; EPE-; PNI+; 8 LN-; SV-
TRT 03/'14- uPSAs: <.015 til 02/17; mostly .020-.030 then .048 on 12/1/18; off TRT since 12/2018 and uPSA settling in mid .030s
Post Edited (Bobbiesan) : 5/19/2019 5:48:21 AM (GMT-6)