The long-term study on a pool of older PCa men (avg age = 70) was published today in JAMA and found:
Among 154,000 older patients, 13% who received hormone-blocking treatment developed Alzheimer’s, compared with 9% who had other treatment or chose no therapy, the study found.
The risk for dementia from strokes or other causes was higher: It was diagnosed in 22% of those who got hormone-blocking treatment, versus 16% of the other patients.
It is possible that the conduit from ADT to dementia may be the blood vessel damage caused by diabetes, or heart disease or depression.https://www.apnews.com/f1412c26dc4c43189099e3165b9901f5
Jan '08-'11 PSAs 2.2 2.5 2.7 2.6, DREs-
Jan '12: PSA 3.6, DRE+
Jan '12: MRI inconclusive
Feb '12: PCaDx pT2a, 4/12+ (3 @ 3+3, 1 @ 4+3); 3% tot cores; bone scan-
Apr '12: RALP; 3+4=7; pT2c pN0 pMx; 30%; 3mm r lat margin of 3+3=6 so pT2+; EPE-; PNI+; 8 LN-; SV-
TRT 03/'14- uPSAs: <.015 til 02/17; mostly .020-.030 then .048 on 12/1/18; off TRT since 12/2018 and uPSA settling in mid .030s