Posted 9/19/2019 9:26 AM (GMT -7)
Matam, Thanks for this post. ADT is almost certainly coming up for me pretty soon. I have a set of bone and CT scans scheduled at the end of October at MSK, then a sit down with my MO. I have just completed an immunotherapy trial at MSK for the past two years (PROSTVAC), but in recent months PSA has taken off:
May '19 2.81
June '19 3.67
Aug '19 4.73
Sept '10 5.04
My highest PSA ever (prior to surgery) in 2009 was 6.0. Hopefully the PROSTVAC did some good, but in either event it is done now. My last treatment was this week. My thoughts in recent months have been that I would want initial ADT to include Apalutamide/Xtandi as the case seems compelling to me. I am approaching (no, galloping towards) age 76, so the thought of achieving around three more years without imaged mets, much less being alive, is more than attractive -- especially as three years is a big hunk of life expectancy at my age.
I think the FDA approval of Apalutamide to treat metastatic, hormone-sensitive cancer is significant -- previous criteria, limited to hormone-sensitive non-metastatic disease, seemed more like a "crack" than a "window" to me. (I need to update my signature below now that I am done with PROSTVAC.) Thanks again for your post. Best wishes. NewspaperLover