An article a few years old, but it provides evidence that PCa has been around for a very long time indeed."A high-resolution CT scan of the lumbar spine region of a 2150 year-old Egyptian mummy has just revealed small, round lesions—the oldest case of metastatic prostate cancer in ancient Egyptians."
The fellow involved died between ages 51 and 60 according to the article, and, as noted, had a metastatic case of PCa.
The article also states that the oldest known case of PCa in an ancient person is the one found in "... the 2700-year-old skeleton of a Scythian king in Russia."
and then adds "... earlier investigators may have underestimated the prevalence of cancer in ancient populations because high-resolution computerized tomography (CT) scanners capable of finding tumors measuring just 1 to 2 millimeters in diameter only became available in 2005."
"The low number of cases (of cancer in ancient remains) prompted a theory that cancer only began flourishing in the modern industrial age, when carcinogens became more widespread."
"But that situation may be changing ... as physical anthropologists gain access to the new generation of high-resolution CT scanners."
It is then concluded that the study of traces of cancer in ancient remains has value, because"there's always the hope that reaching a better understanding of the roots of cancer will help contribute in some way to a cure."
Incidentally, PCa was not officially recognized as a separate disease until
" ... in 1853, J. Adams, a surgeon at The London Hospital, described the first case of prostate cancer, which he discovered by histological examination. Adams noted in his report that this condition was “a very rare disease.” (Well at least he got the discovery
part of it right!) https://www.sciencemag.org/news/2011/10/mummy-has-oldest-case-prostate-cancer-ancient-egypt
Chronic prostatitis (age 60 on)
BPH w/ urinary obstruction, 6/2011
Ongoing high PSA, 7/2011-12/2011
Biopsy, 12/2011: positive 3/12 (90%, 70%, 5%)
Gleason 6(3+3), T1c
No mets, PCa likely still organ contained
IMRT w/ HT (Lupron), 4/2012-6/2012
PSAs (since post-IMRT): 0.1 to 0.3 range