It is not commonly known, but if you have major surgery under a general anesthetic you will experience "mild cognitive impairment" for about a year after.
Most lay people are unaware of the difference between sedation
and general anesthesia.
It all means the same thing to most of us. The MCI, I've come to know much more recently.
BIG difference between sedation used for prostate biopsy or colonoscopy (often Versed, Demerol, Fentanyl) as opposed to General Anesthetics used for surgery. Not only are sedation drugs much lighter duty than General Anesthetic drugs...
Thanks "justwondering" ... It's also good to have the input of a professional, BillyBob.
As I remember you've mentioned in the past that you are or were an anesthesiologist or anesthetist. Having had sixteen major surgeries in my life, I've learned a bit about
anesthesia. Throw in a couple dozen "procedures" done under sedation (biopsies, extractions, placements, etc) I now know the difference. Doctors seem to assume that we all somehow know this.
Soon after my first adult surgery forty years ago (actually two abdominal surgeries back to back) I noticed the profound depression
which lingered for weeks afterwards. Having never had any MH issues in my lifetime, I wasn't sure what to call it. That was a time in my life which I prefer not to dwell upon.
Some years later, I discovered that Methocarbamol, a medication I'd used since childhood for a neuromuscular condition, also started causing a kind of depression. Just within recent years I learned that the commonly used Flexeril
would also send me into depression. And now having been on Effexor for a couple years, and having had six surgeries in just the past three years, I feel like I'm finally getting a handle on the maelstrom going on in my body.
So here's what most people don't know. General anesthesia has three components... sedation, analgesia and paralysis. Please clarify or correct me BillyBob
if I have any of this wrong. The gas makes you unconscious or unaware of what's going on around you. An anesthetic (narcotic) reduces your sensation of pain, a muscle relaxant prevents you from reacting to the pain, and the short acting tranquilizer (Versed) causes you to forget what you've experienced.
I think I've discovered that it is the muscle relaxant
that makes me feel so depressed after every surgery. Fortunately this doesn't occur after "procedures" like biopsies, but it can be induced by Rx oral meds. Recently my GP advised me to "lay off the surgeries for a while" to allow my body to rest (if only it were that simple). I'm still working out what works best for the myoclonic spasms while avoiding muscle relaxants.
Regarding MCI, I don't know just what to blame. It's been nearly two years since my final Lupron injection, yet my testosterone is still at castrate level. Certainly there is some "brain fog" caused by the hypogonadism, and which is not a direct effect of the leuprolide itself. There may be some MCI that goes along with long term use of venlafaxine... I don't know. But life with the V is better than life without it. As mentioned before, I'm all new to the MH aspect of all this. Lately I've been hanging around the chemo brain groups on FB as my brain fog seem close to what the members there experience.
Now I have to count the scars on my body to remember everything that's happened, and it helps if I categorize them as H&N, ortho, GI and GU and count from there. I don't post much here anymore (though it may not seem so) as I'm trying to move beyond my past. Sounds easy, but not so easy to do. Knowing that I am not alone helps. More than anything, I wish that my first Uro and my most recent Uro had treated me the way most of you guys here seem to have been treated. I'm trying to take more personal responsibility for not making better decisions early on... but nobody told me anything. As stated in another thread... No info URO
Yeah, and that person was my first uro.
Trailguy, I identify closely with you here... your age, diagnosis, your wisdom on leuprolide chemo
and your monorchidism
... except maybe your outdoorsyness. I'm pretty lame in that department.
2014-15: PSA's 9, 12, 20, 25, Neg DRE's, false neg TRUS biopsy
6/16: New Uro, MRI Fusion biopsy, 6 pos Rt Base 2ea 15-40-100% G8(4+4)
8/16: DaVinci RP, multifocal EPE, PNI, 11 LN-, 53g/25%, BL SVI, Grp4, pT3b
1/17: Started Lupron ADT, PSA's ~.03
5/17: AMS800 implant, revised 6/17
8/17: 39 tx RapidArc IMRT (70 Gy)
4/18: Dx Radiation Colitis & more
1/18 - 7/19: PSA's <0.008, T~12