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1 year update

Chronic Illness Forums
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Prostate Cancer
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ldog
Regular Member
Joined : May 2018
Posts : 180
Posted 11/7/2019 7:25 AM (GMT -7)
It has been a year since my ldr brachy and I'm now at 1.3. Its going down, but it sure is going down slowly which is weird. I guess I assumed that at 1 year it would be lower, but since its dropping I guess I shouldn't fret?
thx
Born:1962
10/17 psa:5.6
12/17 psa:5.2
02/18 psa:6.3, P2PSA:19.40, PHI:55.35
03/18 Creatinine POC:1.0; MRI:2 lesions both PI-RADS:4. Prostate size:40cc, density: .16
518 Biopsy-Gleason 3+4 with perineural invasion. Tested: NWMH/Epstein.
8/29/18-10/08/19:IMRT (NWMH) (25 sessions)
10/26:LDR Brachytherapy (Moran) (72, I-125 seeds)
02/19 PSA:2.8
07/19 PSA:1.8

Post Edited (ldog) : 11/7/2019 7:46:25 AM (GMT-7)

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mattam
Veteran Member
Joined : Aug 2015
Posts : 1905
Posted 11/7/2019 7:40 AM (GMT -7)
You’re doing well.👍
Part I
2015 (Age 54) PSA: 20.8
Bx: All cores G7 (4+3)
RALP & Adjuvant RT
Pathology: G8 (4+4)+5
PSA nadir: 0.1, steady increase until 2019: 64.13

Part II
2019, March: Lupron/Xtandi, PSA: 1 month: 0.126; 3 months: 0.036; 6 months: <0.02
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alephnull
Veteran Member
Joined : Dec 2013
Posts : 1559
Posted 11/7/2019 7:45 AM (GMT -7)
What mattam said!
And to add, since you still have a prostate, you will always have a PSA.
Time to watch if it rises.


My Biopsy
My PSA Curve
Previous PSA
Curve

Treatment Path
My Story
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MG0351
Regular Member
Joined : Jul 2018
Posts : 262
Posted 11/7/2019 8:08 AM (GMT -7)
Down ward is good....
Congrats..
DX 7/23/18
Gleason 9
Prostate size 44
stage T2B
No mets.
PSA 5.2
6/16 probes positive 2 maybes.
All on right side 1 on the left
Age 65 with lung problems.
HT 8/22/18 2nd 2/28/19 8/28/19 Eligard 6 month shot
UROLIFT 10/24
11/11/18 IGRT/IMRT finished 1/17/19
5/1/19 Right middle lobectomy
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Buddy Blank
Veteran Member
Joined : Jan 2013
Posts : 1628
Posted 11/7/2019 8:20 AM (GMT -7)
ldog mine took what seemed like forever to get down there. It was frustrating, and stressful. I wondered if it even worked, or maybe the seeds weren't "hot" enough, etc.

I've read, don't remember where, that a slow drop is better than a fast one - it was some medical study, not some stranger on the web.

Hang in there, you will get there.
Right prostate: Benign tissue
Left prostate: Prostatic adenocarcinoma, Gleason score 7 (4+3), 2 of 10 cores, 5% of total tissue sampled, Stage T1c, positive for PNI
66 Pd-103 seeds 3/13
PSAs: 4.76 5/12 - 4.23 8/12 - 3.98 10/12 - 4.9 2/13 - 2.9 6/13 - 2.7 11/13 - 1.31 3/14 - 1.07 7/14 - 0.69 10/14 - 1.6 3/15 - 2.0 6/15 - 0.64 8/15 - 0.68 4/16 - 0.16 11/16 - 0.12 6/17 - 0.12 6/18 - 0.04 6/19
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ldog
Regular Member
Joined : May 2018
Posts : 180
Posted 11/7/2019 8:27 AM (GMT -7)
Buddy, I read that too. The article had something to with the aggressiveness of the cancer. And that if it drops slowly that it's not as aggressive, etc.
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InTheShop
Elite Member
Joined : Jan 2012
Posts : 11059
Posted 11/7/2019 9:11 AM (GMT -7)
It can take a long time. You're doing just fine.
Andrew
I'll be in the shop.
Age 59, 52 at DX
PSA:
4.2 10/11, 1.9 6/12, 1.2 12/12, 1.0 5/13, .6 11/13,
.7 5/14, .5 10/14, .5 4/15, .3 10/15, .3 4/16, .4 10/16, .4 5/17, .3 10/17 .3 4/18, .4 11/18
G 3+4
Stage T1C
2 out of 14 cores positive
Treatment IGRT - 2/2012
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JNF
Veteran Member
Joined : Dec 2010
Posts : 4429
Posted 11/7/2019 9:30 AM (GMT -7)
This trend is your friend. It can take five years to reach PSA nadir following radiation as a primary treatment. And throw in a few bounces here and there. Be patient and enjoy life.
PSA 59 on 8-26-2010 age 60. Biopsy 9-8-2010 12/12 positive, 20-80% involved, PNI in 3 cores, G 3+3,3+4,and 4+3=G7, T2b.
Eligard and Jalyn started on 10-7-2010. IMRT to prostate and lymph nodes started on 11-8-2010, HDR Brachytherapy December 6 and 13, 2010.
PSA < .1 since February 2011. Located in Cumming Georgia north of Atlanta
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Sr Sailor
Veteran Member
Joined : Sep 2015
Posts : 740
Posted 11/7/2019 10:07 AM (GMT -7)
Yes, you are doing just fine.
Perhaps your PSA will stay around that level and that would be just fine as well.
Mine has been around 1.4 (after SBRT and IMRT; see my signature) and I am super happy. Thanks to all the professionals who helped me!

Post Edited (Sr Sailor) : 11/8/2019 3:05:46 PM (GMT-7)

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Paxton
Veteran Member
Joined : Aug 2016
Posts : 1294
Posted 11/7/2019 4:53 PM (GMT -7)
ldog - I just met with my uro and RO, and had about the same conversation. My pre-treatment PSA was 5.69, and now, about 3 years out from SBRT, it is down to 1.55. Mine has been a slow and bumpy decline, but both my Uro and RO agree that the slower trend down is a good thing, as are the bumps I have experienced in my journey. Don't fuss or worry, just watch the long-term trend.

Also, remember, it isn't considered a recurrence until it hits your nadir (lowest point post-treatment) plus 2.0. So, in your case, unless your PSA exceeds 3.3, it is just bumping and making noise. (Might make you uneasy, too, but probably not your uro, unless it shows an upward trend.)

Good job. Keep up the good work!

P.S. You have been to the sensei of seeds, at least here in the middle of the States. Trust in him, too.
Age 68 at Dx
PSA history: 2000-2012 0.9-1.2; 06/2012 started T replacement
2013-2015 3.0-3.3 (new normal); 11/2015 4.6; 05/2016 5.7
Biopsy: 12-core biopsy 07/2016; 3 cores G3+3, 5% or less; 1 core 3+4, 15%; 1 core HGPIN; 2% of gland involved. Summary G3+4.
CyberKnife SBRT with Dr. Hirsch; start 11/15/16, finish 11/23
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ldog
Regular Member
Joined : May 2018
Posts : 180
Posted 11/8/2019 7:35 AM (GMT -7)
Thanks all.
Born:62
10/17 psa:5.6
12/17 psa:5.2
02/18 psa:6.3, P2PSA:19.40, PHI:55.35
03/18 Creatinine POC:1.0; MRI:2 lesions both PI-RADS:4. Prostate size:40cc, density: .16
5/18 Biopsy 3+4 with perineural invasion. Tested: NWMH/Epstein.
8/29/18-10/08/18:IMRT (NWMH) (25 sessions)
10/26/18:LDR Brachytherapy (Moran) (72, I-125 seeds)
02/19 PSA:2.8
07/19 PSA:1.8
11/19 PSA:1.5
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Terry's Cellar
Regular Member
Joined : Mar 2017
Posts : 96
Posted 11/8/2019 7:50 PM (GMT -7)
My RO says RT for PCa is a marathon and not a sprint. Every treatment option has advantages and disadvantages. Those of us that choose any of the radiation treatment options don’t get a pathology report; however, all the treatment options have to monitor PSA. That said RT guys usually escape some nasty side effects that the surgery guys can have. My RO also says that PSA can be a bumpy road and that’s not necessarily a bad thing. Bounces are common between 18 and 36 months and happen in about 25% of RT guys. Those guys and those with a slow downward trend tend to do very well in the long run. Nadir may take three to five years to achieve. Good luck. 👍
Rising PSA
11/12 1.98
11/13 1.95
9/15 3.28
10/16 5.94
1/17 3.0
TRUS 1/17
Bx: Three of twelve cores adenocarcinoma Gleason 6 (3+3)
all on left side and <5%, no pni
DOB 7/21/47 good health.
Age 69 @ Dx
Treated with SBRT by Dr. Tendulcar @
Cleveland Clinic 6/23/17
Reduced ejaculate is only side effect. Everything works
PSA’s post SBRT 1.1, 1.1, .9, 1.8, 2.7, 1.0
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