Prior to treatment 7.4. Today 8. Dr said possibly due to inflammation.
Definitely possible. Also, though we don't read much about
it, I have read that dying PC cells dump PSA into the blood stream. So, rapidly dying cells can actually temporarily raise PSA. I remember an 8 week clinical trial I read 6 years ago. In the placebo group and other treatment groups, the PSA- which had been rising steadily in these advanced cases- continued to rise at about
the same rate. In the treatment group, the PSA rose even faster than placebo fo several weeks, and then began falling rapidly as placebo continued the steady rise. So, it appears that PSA can rise as PC cells are first starting to die off.
However, as well as the usual PSA, they used Homocysteine as an another method of measuring tumor load. While this continued unchanged or rose in the placebo group, it dropped from the first week steadily for each of the 8 weeks in the treatment group. So, IF homocysteine is actually a useful method of measuring the amount of cancer, this means cancer cells were dying(indicated by dropping homocysteine levels only in the treatment group) while PSA was increasing. This continued until the tumor had shrunk enough to compensate, with lower PSA production, for the PSA being dumped by the dying cells. Don't hold me to any of that, just something I read a few years back. Also, seems to me I have seen people after radiation have their PSA, after a steady decline, rise for a short time before it started to drop again on it's way much lower. Point is, inflammation or maybe other things might make the PSA rise for a while, even if PC cells are dying. Which I hope is the case.
Post Edited (BillyBob@388) : 1/1/2020 7:24:48 AM (GMT-7)