First go-round with leuprolide chemo was 2 & 1/2 years on and about
2 & 1/2 years to recover my hippocampus/pituitary hormones. I found that the ADT had killed one of my testicles outright - it stayed the size of an almond and my T only hit 340 (originally 750), then dropped to 160 over 12 months. PSA went up to 3.3 so I went back on leuprolide chemotherapy this past Nov. Started Xtandi yesterday as well.
These chemotherapy drugs make profound changes to your body and mind. You can control the situation to a great extent, however.
This presents a great opportunity to make heavy exercise a part of your life. A serious daily exercise routine is very good for you, both body and mind. It calms the emotions, brings a measure of satisfaction with your life and masks minor pain issues. It is also extremely helpful in preventing dementia, an issue for those of us on leuprolide chemo, and in slowing the progress of our cancer.
This round of leuprolide chemo I have enabled myself to feel sexual despite a complete lack of testosterone. Empowering desire to be a purely emotion-based experience rather than hormonal-based feeling is a very enlightening experience.