In an effort to present differing opinions, the following was recently posted by TA (a former contributor to this site) as it pertains to the Prostate Cancer Foundation article (link posted above).
"Yet, drugs that block insulinlike growth factor have been proven ineffectual for prostate cancer. Prostate cancer feeds on fats more than sugars until the final stages, but cancer cells are ravenous for energy and will feed on anything available. You can't starve them by starving yourself of any nutrient. That article is just plain silly."
So the "sugar feeds cancer" controversy continues...
He and I used to battle over that one and several other things. For me his point about
the failure of a drug- even a drug designed to block insulin like growth factor- to be effective against PC - was irrelevant. It is a drug, and who knows how well it works, or even if it causes harm itself, you won't ever really know for many years of usage. And who knows for certain whether "blocking" insulin like growth factor will have the same effect as having lower blood insulin?
But what we do have are decades of studies on type 2 diabetics(T2D) -who are virtually defined by high levels of blood insulin and insulin resistance regardless of what their blood sugars are measuring. And these studies show that T2Ds do significantly worse in all health measures, including ALL cancers, PC included.
Now there was a pretty bad fake out a few years ago when some studies showed that T2D was - get this- protective against PC. So, if we were only concerned about
death from PC and nothing else, maybe we would be better off with diabetes? But I called BS on that one right off the bat. My theory was that men tend to develop T2D way before they do PC. In fact, in our day, what used to be called Adult onset diabetes(T2D) is now showing up in teenagers and even children, possibly due to decades of low fat/ high carbohydrate diets combined with sedentary lifestyles. So we get T2D sometimes decades before PC. And what happens when folks are diagnosed with T2D? They normally undergo treatment and or lifestyle changes for their diabetes. Which if things go well will lead to lower blood sugar and the insulin that normally goes with it. Which, not surprisingly then, leads to protection from PC for that group, compared to the rest of the population who are plugging right along with their somewhat high blood sugar(but not quite diabetic) and their undiagnosed high blood insulin. We have all heard that metformin might be protective against PC. And what does metformin do? Lowers blood sugar and more importantly blood insulin. So, even if insulin like growth factor blocking drugs have not helped with PC, it appears that drugs that actually lower sugar and insulin do. And even better is reversing T2D or pre diabetes with life style changes.
Lastly, though insulin like growth factor blocking drugs may not help anything, several studies of people with high blood insulin indicate that they do worse with PC, just as they do with all other cancers. 3 to 8 times worse. Those are big numbers, bigger than most other risk factors. And that may NOT be specifically caused by the sugar rather than the insulin, but the sugar is what results in the high insulin. The only time our bodies normally produce insulin is when blood sugar must be dealt with. So is high blood sugar diet per se a problem associated with PC? I'm not certain, but it sure is a problem with a boatload of other things that want to kill or disable us, and maybe also for PC. Is high blood insulin(a result of a high sugar diet) a problem with PC? Highly likely.