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Failed Radiation therapy surgery option?

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theswan
Veteran Member
Joined : Nov 2005
Posts : 550
Posted 1/4/2021 1:03 PM (GMT -7)
Hello I have a long running post on my Pca troubles. My RO said urinary retention will most likely return. I had a hellish experience being catherized that led to paraphimosis and was close to necrosis of the glans penis.
My oncologist surgeon Dr Decastro said that he Will do surgery.
I welcome comments from others who have had RP
Due to sleep apnea I assume I'll have an epidural and mild sedation
I really wanted the radiation to work but had the retention after the 4th treatment then had two more but developed the paraphimosis and just could not continue.
I hope we can wait at least a few weeks so I can heal from the paraphimosis which is still sore and my peeing is kinda weak. Thankfully the blood and clots have stopped.

Thanks
Glen Heinsohn
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Pratoman
Forum Moderator
Joined : Nov 2012
Posts : 8399
Posted 1/4/2021 3:12 PM (GMT -7)
Glen,surgery after radiation is a whole different ballgame. Its generally much more complicated and takes someone who is highly skilled, in part due to the scar tissue and other effects from the radiation. I'm just not sure to what extent that applies, after only a few treatments, something to ask your surgeon.
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Sr Sailor
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Joined : Sep 2015
Posts : 953
Posted 1/4/2021 3:27 PM (GMT -7)
How many radiation sessions did you end up having?
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justwondering
New Member
Joined : Mar 2016
Posts : 13
Posted 1/4/2021 3:42 PM (GMT -7)
Correct me if I’m wrong, but I suspect RP is generally a multi hour process with general anesthetic and intubation, the latter precluding apnea issues.
Has anyone had RP with a regional block and “light sedation” which would imply a conscious patient?
Carl
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lapilot
Veteran Member
Joined : Nov 2012
Posts : 913
Posted 1/4/2021 4:51 PM (GMT -7)
Prostatectomy is a complicated surgery that requires general anesthesia. Surgery after radiation treatment is very difficult and requires a highly trained urologist that can accomplish this procedure because of the scar tissue. You should seek out a urologist that has done a number of these procedures. Surgical outcomes after radiation usually have more serious side effects including incontinence, bladder, rectal, and colon issues.
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theswan
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Joined : Nov 2005
Posts : 550
Posted 1/4/2021 5:20 PM (GMT -7)
I think I had 5 treatments out of 55
My surgeon knows what I've been through and has said he may do surgery. I ran into him because his staff wrongly scheduled me so it was a brief encounter.
I also am guessing about the epidural and mild sedation but have read about it taking place.
I Am between a rock and a hard place. My penis is slowly healing but it's still raw and my urine flow is weak
The RO said urinary retention will most likely return. Seems I have little choice.
The RO said he'd call Dr Decastro about my choice. I will call the office tomorrow and see what my next move is.
I wish there were other options.
I'm scared to death and can only pray that Dr Decastro will do the surgery

G
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theswan
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Posts : 550
Posted 1/4/2021 5:25 PM (GMT -7)
BTW Dr Decastro is Harvard and Columbia trained MD and professor with many years of practice. I assume he is qualified

Glen Heinsohn
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halbert
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Joined : Dec 2014
Posts : 5034
Posted 1/4/2021 5:34 PM (GMT -7)
epidurals are used for things like fusion biopsies and TURP procedures. RALP is done under general anesthesia, with all kinds of fun things like being on a tilted table in what is called the reverse Trendelenberg position...basically at a 45 degree angle head down.

You'll be intubated, and the anesthesiologist is keeping you alive. The surgery for an uncomplicated case takes 2 hours or so...and yours likely is not uncomplicated. I don't know how much damage your relatively few zaps has caused...that is a question for your whole team to look at.
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theswan
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Joined : Nov 2005
Posts : 550
Posted 1/4/2021 5:51 PM (GMT -7)
Nice to hear from you Halbert. I Was only guessing about the epidural and mild sedation. I forgot the intubated to breathe part
That should not be a problem because I'm sure they take into account the sleep apnea issue. I am 68 years old well on the 13th I'll be 68 I'd have to stop my Xaralto blood thinner but I at least feel strong as an ox and that should help.

I'm pretty sure that the doctor agreed already but my focus at that time was all about "thank you doctor I can pee again and the pain stopped " he said I was close to losing my glans penis so the surgery piece was not upmost in my thoughts

Glen Heinsohn
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jasperx10
Regular Member
Joined : Nov 2018
Posts : 141
Posted 1/4/2021 6:53 PM (GMT -7)
Hi theswan.
You mentioned earlier problems with being catherized. You have my great sympathy - can be terrible painful. Check with your doc on how catherisation will affect you on the surgery. You'll need it for at least a week if all goes perfect and it's key hole surgery. Maybe even longer - 10 days-2 weeks. Mine was 3 weeks but I had open surgery which requires a little longer time. If you had a problem with the catheter on a previous time, check if a smaller sized one will help this time. I had major problems with my catheter following surgery and when I went back for corrective surgery to fix the resulting stricture, the urologist used a smaller catheter.
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halbert
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Posts : 5034
Posted 1/4/2021 6:56 PM (GMT -7)
Yeah, Glen, that is a thing: After surgery a catheter is guaranteed for at least a week, or longer. Make sure you get an understanding from your doctor how to prevent what happened last week. And then do it. I know I was told to at least daily apply bacitracin or something similar to the catheter at the tip to keep things moving and prevent adhesions. I also had a tube of an anesthetic gel to use to prevent pain from the abrasion.
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Mumbo
Veteran Member
Joined : Nov 2018
Posts : 1093
Posted 1/4/2021 7:42 PM (GMT -7)
Glen - I previous mentioned that my 93 year old father was circumcised at 85 due to continuing problems he was having that sound similar to what you experienced. You may have a potential problem that could cause future issues so maybe a repair might be required? He said it was not a big deal afterwards which is hard to imagine.

Surgery clears up a whole lot of urinary problems although the problem is that the off switch often gets damaged so you have to be careful what you wish for. I had virtually no issues with continence which seems to be unusual but not everyone takes a year to recover either. It is the big unknown after surgery followed by the ED issue so keep those in mind in your discussions with the best surgeon you can find there.

Good luck fighting your way through this difficult situation.
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theswan
Veteran Member
Joined : Nov 2005
Posts : 550
Posted 1/4/2021 8:07 PM (GMT -7)
Thank you all.
The catheter issue was partly caused by not pulling my foreskin over. It became a paraphimosis. Dr Decastro said that my foreskin split and I am applying bacitracin to it and cleaning the area. I Am not afraid of the catheter as much as the possible side effects. I've had them after surgery before but this was not normal.
I'm not blaming the nurse who put it in. I blessed her because I was so backed up and it was a relief. Maybe I should have been more vigilant and will be next time. I left the ER with no instructions other than see my urologist

Glen Heinsohn
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theswan
Veteran Member
Joined : Nov 2005
Posts : 550
Posted 1/5/2021 2:52 AM (GMT -7)
Up at 4:30am peed into a quart container because my wife was using the bathroom. I noticed an ammonia smell
Not overwhelming but evident. I filled the whole quart so I guess that's a good thing.
Try to go back to sleep. I am going to urinate about 15 times a day. I always seem to get the urgency part but usually do not pee too much. Still a little sore but getting better

Glen Heinsohn
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theswan
Veteran Member
Joined : Nov 2005
Posts : 550
Posted 1/5/2021 7:25 PM (GMT -7)
I did not call the doctor today. I am a little too emotional to hear bad news. I am quite frankly a bit of a wreck. My usual chronic pain has me in the apartment most of the day and I am unusually tired. Maybe a UTI since my urine stinks. I am ordering a walker to use to get to the bathroom as I can hardly walk with the hip and back pain
I will call the office for an appointment tomorrow
I Am pretty sure the doctor will agree to surgery but have that usual fear that they May say there's no hope.

Glen
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theswan
Veteran Member
Joined : Nov 2005
Posts : 550
Posted 1/5/2021 7:27 PM (GMT -7)
Oh thankfully the pain improves after several hours and a couple of buprenorphine tabs

G
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Paxton
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Joined : Aug 2016
Posts : 1375
Posted 1/7/2021 8:57 AM (GMT -7)
Glen,
I would not worry too much about the warnings you've gotten about surgery after radiation treatment. The issues that occur after radiation refer to surgery after completion of a full radiation regimen, not the 5 or so treatments (out of 40-50) you have had. Also, with any type of radiation, the effects on the prostate are not seen immediately after treatment. It takes a while for the radiation to do its "intentional damage" so if you were to have surgery very soon after the few radiation treatments, your chances would be better of having the same experience as any "surgery only" patient.

Note that I am not a doc, but am just thinking logically. If others have additional or better insight, please join the discussion.
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theswan
Veteran Member
Joined : Nov 2005
Posts : 550
Posted 1/7/2021 9:16 AM (GMT -7)
Thanks Paxton thanks a lot.
Update. I dropped off a urine sample to test for infection. It smells more normal today but still thick or dark
Been drinking green and herbal tea and some distilled water I usually use in my CPAP machine.
Ran into the RO.Dr Deutsch who said TURP may allow me to continue radiation treatment. It will allow me to keep retention at bay.
I see the surgeon tomorrow afternoon and will see which is best TURP or just remove the prostate
I do trust the surgeon. He is very well educated and has rave reviews. I lean toward TURP followed by radiation but will wait to see what Dr Decastro says

I Am grateful to be able to write here. It helps not only to educate but supports me emotionally which I really need. A positive attitude is important. Right now I feel almost but not quite depressed but gain the important quality of compassion and hope when I come here

Glen
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theswan
Veteran Member
Joined : Nov 2005
Posts : 550
Posted 1/8/2021 7:04 AM (GMT -7)
My appointment is at 4pm

I am mulling over choices. TURP looks like fairly major surgery so I'm thinking why not just have it removed? TURP followed by radiation therapy? The what ifs? Is TURP really going to avoid the problem with retention? I think TURP followed by radiation is best but not if after a few treatments I'm back to needing surgery
Maybe just get it out. To Add- ED is not a concern nor is wearing a catheter for weeks. Some dripping would be okay. I just worry about a lifetime catheter
Sorry just scared and unsure

Glen
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halbert
Veteran Member
Joined : Dec 2014
Posts : 5034
Posted 1/8/2021 7:49 AM (GMT -7)
Glen,

I'll weigh in here. From the start of your journey, with your retention issues that go way back, I was one who always felt that surgery might have been your best option. The reality is that relatively few men have the permanent leakage issues that are at the front of you mind. It's a bell curve, and the no continence group is at one end of the curve. Yes, it can happen, and it sucks if you're one of the ones at that end. It's not the end of the world, though, there are options. AUS is an option, as well as installing a sling is an option.

For men with large prostates, who already have significant issues with BPH, I think RALP should be much higher on the radar for them--because it will immediately resolve the BPH. Is there risk, of course there is, there is with any treatment plan. I just happen to think there is way too much fear-mongering anti surgery for any reason going on in this forum--at least some of the time.
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DjinTonic
Veteran Member
Joined : Dec 2019
Posts : 1154
Posted 1/8/2021 8:01 AM (GMT -7)
I had a (successful) TURP for BPH in 2013. Four years later my (prostate-confined) PCa was diagnosed and I opted for surgery, with an excellent outcome (so far, at least). If I had a crystal ball in 2013, I would have gladly had my prostate out then to resolve both problems.

In several years of perusing journal articles on PCa, I haven't come across a single study on the effect that radiation therapy for PCa has on BPH symptoms.

Djjn
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theswan
Veteran Member
Joined : Nov 2005
Posts : 550
Posted 1/8/2021 8:55 AM (GMT -7)
Thank you both
I am scared and that makes my thoughts run to extremes. However the thought of just getting it over and done with seems more appealing. I will have much better information in a few hours.
I'm thinking why risk a possibility of two surgeries when one will remove the prostate and may be the end of the problem . Your information and concerns mean so much and lift my spirits.
My wife is supportive but does not understand what and wherefore of this decision. She just does not want to lose me. Sex is no longer an issue with either of us so that is a good thing. We have an affectionate relationship and that is more important than the actual act
Anyway God bless all of you.

Glen
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halbert
Veteran Member
Joined : Dec 2014
Posts : 5034
Posted 1/8/2021 9:09 AM (GMT -7)
Djin, At least my non-scientific data from many comments here suggests that radiation frequently does have BPH side effects during treatment--which makes sense: The radiation causes inflammation of the prostate, and swelling of the tissue, which would aggravate BPH, as we have seen in swan's case.

I know there is concern of surgical side effects when the prostate is large--it's harder to separate the nerve bundles, for example, and the risk to the bladder sphincter is also higher, but, what's the guy like swan to do, if he has a large prostate, BPH, and the need to treat for cancer. The choices are all bad.

Glen, let us know what the Dr. says this afternoon. And, we're with you, regardless of your decision.
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samster
Veteran Member
Joined : Oct 2011
Posts : 595
Posted 1/8/2021 9:28 AM (GMT -7)
Morning Swan,
For what it's worth, I had an epidural with open RP Surgery. My surgeon did not want his patients to deal with being nauseous, vomit, sore throat etc.
No issues.

Samster
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DjinTonic
Veteran Member
Joined : Dec 2019
Posts : 1154
Posted 1/8/2021 9:39 AM (GMT -7)
Halbert, yes I'm aware of the anecdotal reports that some experience BPH exacerbation after RT. But men with BPH making PCa-treatment choices deserve data on the accepted levels of evidence in medicine.

For what it's worth, my prostate was 64 cc when removed and my surgeon said he encountered no problems removing it while preserving both neurovascular bundles.

Glen's is a complicated case and he would be well served by consults at prostate centers of excellence. Of couse if one is told that both RT and surgery are viable options, at some point it does come down to a personal decision one has to make.

Djin
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