Posted 9/28/2021 9:34 AM (GMT -6)
Hello, Jerry ----
Back with you this morning, my comrade ...
Earlier in my treatment plan, my oncologist noticed that LUPRON wasn't knocking down my testosterone levels.
That suppression is important, for my case, because testosterone provides FUEL FOR THE FIRE, in terms of prostate cancer cell proliferation for cases like mine.
So --- he began tracking not only PSA levels, but testosterone levels, which some doctors fail to do.
Honestly, for any fellow here pursuing ADT treatments, make sure you insist on a testosterone test when you run your PSA tests. There's a CONNECTION there.
So --- my oncologist suggested FIRMAGON next. That didn't work any more effectively.
Last of all --- we tried ZOLADEX.
The consistent drop in testosterone levels helped LOWER my testosterone, which helped STABILIZE my PSA levels.
I actually prefer ZOLADEX, and tolerate it better. Whatever works!
It was EASY to switch to other forms of ADT --- but I had to wait before the previous injection waned and "expired" before switching. It made a significant difference for me.
This is a topic that you can certainly cover with your oncologist. They must take the lead on decisions like this.
After chemotherapy, some oncologists will give ZYTIGA or XTANDI a second try. Again, a topic for your oncologist, of course.
My best advice ---- you have had FULL-STRENGTH chemotherapy infusions.
Going forward, there ARE different formulations, in lessened doses, that can be given.
When I see Dr. Kwon at Mayo Clinic, he talks about mixing different strengths and formulations of chemotherapy infusions. He calls these his "chemotherapy cocktails" ... individualized chemotherapy.
I think it's well worth your time to discuss a "lessened dose" of chemotherapy, as a possibility.
You've been through a great deal lately, and I think this idea might be a viable option. Ask your doctor if this is a possibility!
One last thing ---- is it possible to seek out input from another oncologist, for your case?
Records, treatment history, and scans can be shared SO easily --- electronically. Basically --- seeking another expert's thoughts on what a NEXT STEP might be ...
My local doctor shares EVERYTHING with Mayo Clinic, and Mayo Clinic shares EVERYTHING with my local team.
I consider my team at Mayo Clinic my "second set of eyes" watching over my case, and all aspects of my treatments. It's a layered, multi-leveled tier of healthcare, and I feel fortunate to have this team helping me maintain my health goals.
My case has had complexities, as your case does, as well --- so these are some ideas to consider, and then discuss with your doctors.
Wanting all the best for you, Jerry!
With my best,
CYCLONE --- # Iowa State University