Stats such as these are why my uro told me he's optimistic: for us G9 men, if there is highly aggressive tumor left behind (local or distant), you would expect it to reveal itself relatively soon after surgery. When we got the 0.032 recent reading, my uro thought it was probably an outlier, but if I have recurrence now he thought it was more likely to be low-grade located in the pelvis rather than high-grade/distant mets. But again, ya never know!
This is the very discussion I have been having with my URO and now my RO. Though I have without question joined the BCR crowd(as a G9 with 1 focal positive margin and + SV, not great), I made it 6 dang years before the rise began with a vengeance. I have now had 2 auxumin(sp?) scans first one about
6 or 7 months ago showed zilch. 2nd one a month or so back showed a "tiny but suspicious" area on the aorta and an even smaller "suspicious" area on the iliac crest. But still showing zilch in the prostate bed. I have been discussing having the RO play whack a mole with focal RT for the suspicious spots, but he is not certain they are well enough identified to hit them. And both docs seems to think that PSMA scans will be here any day now, so we are trying to wait on that. But if they don't hurry up and get here, he may just have to take his best shot.
But a big part of this discussion has been: how aggressive is the remaining cancer likely to be if it has taken over 6 years ( 7 now ) to rear it's head? By some studies ( which as Logo said "my son...a epidimiologist at Chapel Hill is..." all studies are wrong ".), , some of which you have quoted, even high risk with BCR past 3 years have a way lower chance of dying from PC. ( but, of course, not zero). Heck, I was < .01 for 18 months, then .01 for another 18 months, then .02 for a year or 2, finally .03 for a year or so. Then the rise began, and suddenly, at about
6 years, I am a BCR. So, the length of time that took seems in my favor, and has been a big point made by my URO and RO, but the rate of sudden rise is disconcerting to say the least. Almost all of it has happened in the last year. Come on PSMA, or I might have to go on without you very soon.
Post Edited (BillyBob@388) : 7/15/2021 3:38:37 PM (GMT-6)