Here is an online sample Decipher sample report in color. Of course your numbers will differ. You can see the high-risk red zone goes from 0.60 to 1.0. IMO your doc should have given you the original and kept a copy.
On the right are three percentages:
High Grade Disease (primary Gleason grade 4 or 5) ___
5-Year Metastasis ___
10-Year Prostate Cancer Specific Mortality ___
The first is the risk that you currently harbor a lesion with a primary grade of 4 or 5, i.e, higher than those of any of your TURP samples exampled also higher than a G7 (3+4). In other words, the chances that you currently have a lesion anywhere from G7 (4+3) up to G10 (5+5). The first number in a Gleason score is the primary Gleason grade and represents >50% of the cancer, so a G7 (4+3) is more serious than a G7 (3+4).
The next two percentages are *within* the stated period: the statistical risk of metastases within 5 years and the risk of dying from PCa within 10 years.
You should not rush into a decision, especially if your are a Gleason 6! Take your time, get a second opinion on your pathology, consult with a radiologist who specializes in PCa treatment, perhaps other surgeons. Personally, even if Dr. Epstein confirms you G6 status, I would opt for treatment to the exclusion of active surveillance in light of the Decipher results.
Unfortunately a biopsy (including that done on TURP tissue fragments), can miss higher-grade cancer. If your Decipher score is high, it means there is a risk more serious cancer lesions can form at any time, or have already started to form.
That report looks somewhat different from mine. Could that be because that is from Epstein and mine isn't? Not even sure that is a valid question. lol
Mine has these parameters:
5-Year risk of Metastasis - 1.5% }
10-Year risk of Metastasis - 3.5% }
15-year Mortality Risk - 2.8% }
Risk of Adverse Pathology - 40.6% }
So, mine shows 5 & 10 yr risks - with those low %, does that indicate I am low risk of having that occur? Same for mortality - seems like it is saying 2.8% of guys in my category have a 15 yr mortality. Is that how I read that?
Is the Risk of Adverse Pathology = High Grade Disease? Doesn't seem to be the same score so not sure how to interpret some of your clarifications But then again, Mumbo indicates it is...so, I don't know! Or should I say "I'm so confused!!"
Mumbo, thanks for the guidance on the MRI machines, I will definitely address that with my dr when we set the MRI appt.
And you are right, I am the type of guy that would worry so I will NOT sit on this and ignore it. I want a full life and I am very healthy aside from this dastardly diagnosis. I want to live and enjoy my life. I know what happens to me when I die but for now, I have a wonderful wife and love my life so I will not put it at risk by not taking action. That is still down the road a few months so I know I have time. And as Djin stated, I will not rush into a treatment, especially something as radical as RP. I think I will also get a 2nd opinion from a friend's doctor (Dr Eric Klein) who is the chief of prostate and other cancers at Cleveland Clinic in Cleveland. He is working on getting me a consult as that is his doctor.
Once again, you guys are amazing and I so appreciate your input, although, Djin's was a bit sobering. LOL. Even so, I still greatly appreciate you guys.