As we know, the the "official" PSA definition of BCR is 0.2 and rising, but Johns Hopkins docs originally proposed 0.4, because some men have a rise that then plateaus. The consensus is that the later
, BCR occurs and the slower
the rise, the better the prognosis.
I would even wager that you won't reach 0.5, and even if you do, it may be at an age when it's not a pressing matter or could be treated with ADT alone. The time from BCR to clinical recurrence is 3-8 years, with the average around 5, if I remember correctly. Many men with BCR do not go on to clinical recurrence (detectable lesions), but younger men generally treat BCR out of caution).
PSMA scans are changing the picture, and I, too, may wait beyond 0.2 should my PSA increase.
Post Edited (DjinTonic) : 6/17/2022 9:45:28 AM (GMT-6)