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Active surveillance

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Prostate Cancer
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DJL21
New Member
Joined : Dec 2020
Posts : 15
Posted 11/25/2022 8:59 PM (GMT -8)
Anyone on active surveillance with 4 cores G6?
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centralPAdude
Regular Member
Joined : Jan 2022
Posts : 146
Posted 11/26/2022 1:37 AM (GMT -8)
Hi DJL21, some questions…
What percentage of each of the cores were G6?
How many cores sampled?
Were the positive cores targeted by MRI? Or random ones?
PSA trend?
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DJL21
New Member
Joined : Dec 2020
Posts : 15
Posted 11/26/2022 11:15 AM (GMT -8)
5,5,10,15%
15 samples. 3 for targeted lesion. Those 3 benign. So 4 of the other 12 positive.
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DJL21
New Member
Joined : Dec 2020
Posts : 15
Posted 11/26/2022 11:17 AM (GMT -8)
PSA 3.66 to 4.06 in about 2 years.
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mattam
Veteran Member
Joined : Aug 2015
Posts : 3992
Posted 11/26/2022 11:29 AM (GMT -8)

DJL21 said...
PSA 3.66 to 4.06 in about 2 years.

DJL21,
For me, that stat alone would make feel reluctant to pursue anything other than AS. Some prostate cancers put out low PSA increases, but your other indicators don't point that way at all.

What does the Uro say?
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mattam
Veteran Member
Joined : Aug 2015
Posts : 3992
Posted 11/26/2022 11:43 AM (GMT -8)
PS,
I guess maybe you're on an AS plan but are wondering if it's the right thing to do?
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centralPAdude
Regular Member
Joined : Jan 2022
Posts : 146
Posted 11/26/2022 3:47 PM (GMT -8)

DJL21 said...
5,5,10,15%
15 samples. 3 for targeted lesion. Those 3 benign. So 4 of the other 12 positive.


That’s eye catching.

What percentage of those 4 were G6? Definitely a difference between 5% each and 95% each. Were they all on the left or right side? Or spread out?

Your PSA density is another metric to consider. You could also have your biopsy analyzed for genomics.

These are all things I would consider in an AS decision, but it sounds like you are in the middle of the AS range.
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