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Posted 10/30/2006 4:06 PM (GMT -8)
Hi, my husband got his results today and I am
wondering about a 2nd opinion. The urologist
said 1 core out of 12 was slightly suspicious, and something called PINS.
He recommended a repeat biopsy in 6 mo which my husband really doesn't want to do as the 1st was painful. The urol. said he could have it done in the OR. Does someone out there w/PINS
know if this is the routine? I am wondering about a 2nd opinion , maybe from someone younger and more familiar w/new techiques, etc.
Although this sounds like a abnormal cell
pre-malignant state, I wonder if we can turn it
around w/lycopene, selenium and pomegranate?
He is also taking Zyflamend, an antiinflamitory.
thanks for any info.
Jwife
Posted 10/30/2006 4:27 PM (GMT -8)
Jwife... I'm not sure about this..... but Swimom will catch this soon and she will be able to help guide you!! It will be helpful if you go ahead now and add more specifics... so they are visible on this Thread.
Age
PSA
Gleason
and anything else you have on that report that can help her .... to help you!!

Swimom ~ Thank you for you!!!! You are a "special guardian angel ~ to all of us with your wisdom".

smile Lee
Posted 10/30/2006 5:05 PM (GMT -8)
Tell your urologist to send the slides to Jonathon Epstein, M.D., the most renowned prostate pathologist in the country, for his review. Epstein's at Johns Hopkins in Baltimore. Every urologist worth a grain of salt knows of Epstein, whose lab receives dozens of slides via overnight delivery every day for second opinions. That's where my slides went for second opinions (twice) and I'm glad they did. You will have piece of mind after Epstein's opinion.
Posted 10/30/2006 8:11 PM (GMT -8)
SJC has it right Jwife.

Send the biopsy slides to Epstein at Hopkins for a second opinion. Most cases are rebiopsied 6 months to a year down the road, especially if there is an increase in a man's PSA.

PIN or prostatic intrapithelial neoplasia affects the cells that line the ducts of the prostate. PIN is in of itself, not cancer but is often found in the area where cancer is found. PIN is much more likely to become cancer so it does warrent watching. There are plenty of theories out there that say it can be held at bay with diet changes so keep up the good work! I sure wouldn't rush out and have surgery but I'd be cautious. Remember, PIN is not cancer and it may never be! Good Luck, Swim
Posted 10/31/2006 7:02 AM (GMT -8)
Jwife,

Swimom and SJC are right on track. My biopsy came back with 1 in 10 core samples with 40% cancer and a Gleason of 3+3. I went to a university based medical center and they got the slides and their pathologist read it as "atypical". The urologist at the medical center personally knew Dr. Epstein and sent the slides on to him and he confirmed the original read. I actually got the report with Dr. Epstein's signature so I felt better that there had been no mistake in reading the slide.

Tamu
Posted 11/1/2006 4:35 AM (GMT -8)
thanks for all your replies. Maybe it's not the
slides I question but the followup. I read not
long ago that waiting /watching shouldn't be a choice. My husband's PSA was 4.05
and there was no gleason score. They only do a Gleason score if the cell findings were malignant.
I don't have this Epstein's address, do one of you?
Jwife
Posted 11/1/2006 5:07 AM (GMT -8)

Jwife,

Consult slides can be sent to: Johns Hopkins Medical Laboratories 1620 McElderry St. Reed Hall Rm 315 Baltimore MD 21205.  They should be able to answer questions on their Customer Service line at 1-800-997-5475.  If you check http://pathology.jhu.edu you should be able to link to online instructions.

Boo

Posted 11/1/2006 5:40 AM (GMT -8)
Jwife:

I recognize some anxiousness in your comments. We all had them at one time or another. However, once we educated ourselves the future decisions we made were much easier to handle. I gained a lot of knowledge from a paperback book by Patrick Walsh, M.D., entitled "Guide to Surviving Prostate Cancer". The book was printed five years ago, so it is dated in certain respects; however, it provides an excellent chapter on screening and detection, which I think is your primary concern at this point. After reading the book and the pertinent chapters of interest to you, I believe you will understand why your urologist suggests a repeat biopsy in six months and why three of us on this thread all suggested to you to send the slides to Dr. Epstein, a pathologist we hold in reverence.
Posted 11/2/2006 4:25 AM (GMT -8)
thanks for your replies.
We will consider your
suggestions.
Jwife
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