Atypical biopsy diagnosis question for Swimom

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Regular Member

Date Joined Oct 2006
Total Posts : 27
   Posted 12/15/2006 1:33 PM (GMT -6)   
If you don't mind my asking, I'd like to know what happened after your husband got the "atypical" biopsy diagnosis and you spoke to Dr. Epstein about it.  Was another biopsy required?  My 2nd biopsy came back with a malignant diagnosis so I sent it to Johns Hopkins for confirmation.  Focus of atypical glands was what they reported and recommended another biopsy.  Dr. Epstein was out of town but I can talk with Dr. Partin about it at an appointment I have next week. I'm not quite certain what to make of these differing biopsy opinions or even what questions to ask.  Maybe some of us just have to be pincushions for a while.  Thanks.

Post edited to add a title to this thread J


Post Edited By Moderator (bluebird) : 1/5/2008 7:28:52 PM (GMT-7)

Veteran Member

Date Joined Apr 2006
Total Posts : 1732
   Posted 12/15/2006 2:06 PM (GMT -6)   
Hi Boo,

No additional biopsy. Epstein also found one tiny focus of 3+3 to go with the 3 atypical foci. U of M and Epstein were identical in their biopsy readings.
At 48, and with a location in the mid base and apex, waiting would only insure one ulcer! Treatment was necessary whether it be now or later.
The tumor burden = 16% of the gland at final pathology. That isn't so tiny a cancer. 16% of a 42 gm prostate isn't big but it isn't small. Imagine what it would have been in a 25-30 gm prostate? Probably positive margins at the apex...yikes! Paul made the right decision. Age and location were definately major players.


Regular Member

Date Joined Oct 2006
Total Posts : 27
   Posted 12/15/2006 2:28 PM (GMT -6)   
Thanks for the quick reply. None of the foci on my JHU report were positive so I guess I'll wait till Tuesday to see what happens next. Oddly enough I scheduled the appointment originally to get a second opinion about what looked like certain surgery. Back on the merry-go-round.
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