Hi Ms. Kat!
Ready for another long dj post?
I have experience with the MUSE. My doc had been having me use Viagra (neither Cialis nor Levitra did anything, positive or negative, for me, whereas Viagra just sort of made things plumper, but not firm) and the pump before my first post-op visit. At that point, three months after surgery, he added MUSE. It comes in a variety of strengths, the top two being 500 micrograms and 1000 micrograms. The suppository is maybe a little less than the size of a sesame seed and it is applied with what someone in the forum called a Barbi baster.
Since we are all friends here, I can tell you how it works. You urinate first to moisten the inside of the urethra, then stretch the penis as far as you can and hold it, and slowly insert the baster (not that uncomfortable because it's pretty thin) to its limit. You then push this button on the outer end of the baster, and it extrudes the suppository into the urethra. You then massage the penis to get the suppository to melt and be absorbed. Then, if it is going to work, waiting time is about the same as for a Viagra.
I have used it maybe a dozen times, the 500 dosage three fourths of the time, and when this didn't do anything, the 1000. I told my doc it didn't do anything noticeable above and beyond the 100 mg Viagra's effects. The first time it made the urethra a little sore, but not bad and not lasting (as my doc said it just let you know it was there). From his giving me this, it seems he is a bit more conservative in advancing from pill and vacuum therapy to this, instead of right to the shot. His nurse said it may not work consistently, that I had to try it several times. She also said don't combine MUSE with Viagra, because of her concern for priapism. I told her, no chance of that, and asked if I could use a lower dose (50mg) of Viagra and the lower dose of MUSE. She said to be careful. As I expected, nothing doin'. Then I tried 100 mg of Viagra and 500 mikes of MUSE and still nothing doin'.
Now, I don't know if I have given Viagra and/or MUSE a fair trial. I wasn't really expecting much, because of the one-sided nerve injury and reconstruction (splicing). A guy seems to need 2 working nerves to get maximum benefit from the pills or the MUSE. I mostly have been using these to test how well the nerve was healing. But, I was recently disappointed to learn that, in order for the nerves to heal optimally, AND for pills such as Viagra to work, you have to have a normal level of TESTOSTERONE, which I don't (see http://www.bcm.edu/news/item.cfm?newsid=817).
I am going to have my second post-op PSA drawn this week (crunch - the sound of nails being chewed), and then, God willing that it is still undetectable, I have an appointment to see Dr. Lipshultz at Baylor at the end of the month to see if I can start testosterone replacement again. Then, I can put this theory to the test and see if a) it helps the nerve heal faster, then b) if it causes the Viagra and the MUSE to work as advertised, and then c) see if this wakes up Mr. Happy.
If not, then I think my doc is going to ask me to consider the shots, to avoid scar tissue forming, in addition to throwing cold water on Mr. H.
So, there you have a definite MAYBE about MUSE. I think MUSE is like chicken soup. It couldn't hurt (relatively speaking!), except if your insurance doesn't cover it. If you have any questions, please ask.
All the best,
PSA (10/04): 2.9; PSA (2/06):4.4, on Androgel (serum T about 450) at age 56; negative DRE, no symptoms.
PSA (5/06):5.7 with a free PSA% of 8, OFF Androgel (serum T 163).
Biopsy (5/06): 4/12 samples positive; postitive samples only on right side; max Gleason 4+3=7 (in 2 of the 4 -from area nearest bladder. One was 40% of sample, the others less than a mm. thick.
DaVinci robotic-assisted laparoscopic radical prostatectomy + bladder lift + Right nerve plastic surgery (8/23/06).
Catheter out 4 weeks postop, due to internal pinhole leak at bladder-urethra junction.
Pads-Not needed after about 2 weeks post-cath, but gotta go a lot more often.
Final pathology report:T2c-both sides,but in capsule; neg. margins, neg. lymph nodes, neg. seminal vesicles; final max Gleason still 4+3=7.
1st Follow-up PSA (11/7/06): <0.008 !!!; serum T: 195 - still OFF Androgel (at present). Low T may delay return of erectile function (in presence of one damaged nerve).