Recent Prostate Cancer Research & Studies Relating to Treatment Options

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Regular Member

Date Joined Oct 2006
Total Posts : 444
   Posted 4/19/2007 3:38 PM (GMT -6)   
I came across this first article and thought it would be helpful to start a new thread relating to recent prostate cancer research and studies that might be significant in terms of deciding on a treatment.

Protein Triggers New Targeted Prostate Treatment
Scientists have developed a potential new type of targeted therapy for prostate cancer, which is activated by a protein made by the cancerous cells themselves


Note from Dave:  While I think it is useful to read this study, it does not give enough details relating to side effects.  Again, as I have said above, external beam radiation is a broad radiation term.  Based on my research, I believe that patients who are treated with the more sophisticated forms of beam radiation today (i.e.,  IMRT or IMGT x-ray radiation and proton radiation), may experience lesser side effects than patients who are treated with branchytherapy. I believe that branchytherapy patients experience more profound urinary side effects after treatment than those treated with radiation therapy.  I suggest that you do your own research on the internet to arrive at your own conclusion. 




Post Edited By Moderator (Admin) : 7/7/2008 12:04:21 PM (GMT-6)

Regular Member

Date Joined Oct 2006
Total Posts : 411
   Posted 4/19/2007 5:19 PM (GMT -6)   
that's interesting! had never heard of a urine test for PSA3.

will have to ask our doc tomorrow about this. (not that it matters now) ... but would just be interested what he says about it.

Ken had THREE biopsies, would have been nice to know about this breaking medical news a while ago :)
Age: 63
Diagnosed: 10/30/06
PSA: 3.7 (up from 3.4 previous year)
Biopsy: 1/10 cancerous, 5% of one core, right apex.
Gleason: 3+3=6
Da Vinci: April 10, 2007
Path results: 1% of prostate involved. Very small tumors on both rght and left apex. Negative margins. Gleason 3+4=7.

Cedar Chopper
Regular Member

Date Joined Mar 2007
Total Posts : 432
   Posted 4/27/2007 4:29 AM (GMT -6)   

Thanks for the data Dave!

I would add that the differences in results between Proton Beam vs. Surgery are likely skewed

by which patients are more likely to choose one procedure over the other.

Thanks Again.  CC

2 Years of PSA between 4 and 5.5
Biopsy 23DEC06 
Only 5 percent cancer in one of 8 samples.
Gleeson 3+3=6
Radical Prostatectomy 16FEB07 at age 54.
1+" tumor - touching inside edge of gland.
Texas Hill Country
FRESH Produce Department Manager
Have you had your 5 colors today?

Veteran Member

Date Joined Feb 2007
Total Posts : 1219
   Posted 4/27/2007 6:54 AM (GMT -6) were a researcher/doctor in a former life, yes?

I wondered where you were and now I know...

You do so much for all of us here, just want you to know it's appreciated.

Hope this finds you well,

Husband Diagnosed 11/17/05 Age: 63 No Symptoms
PSA: 7.96, Positive DRE
Biopsy Right: 6 of 6 Cores Positive Biopsy Left: 1 of 6 Cores Positive
Gleason: 4+3 = 7 Stage: T2B N0 MX
2/09/06: LRP Restage: T3A NX MX
3 mo. PSA Post Surgery: 11.8, 12.9, 13.9 Bone scan, CT scan, Endorectal MRI, Chest XR - neg.
9/06/06: 6 mo. PSA: 18.8 CT shows distant lymph node involvement Start HT Lupron 3 mo. shots
12/06/06: PSA 0.8
03/07/07 - PSA 0.3

New Member

Date Joined Apr 2007
Total Posts : 7
   Posted 4/27/2007 10:52 AM (GMT -6)   

Thanks for the information PcDave.  I will be asking a lot of questions at my followup on 16 May based on the PCA3, ASGP1 and ECPA2 research.


DIAGNOSIS: . Age 59. PSA 4.6. PSA free 2%. Clinical pathology: Gleason 10. Stage T2a.           
SURGERY: 23 March 2007. RP at Hackensack Medical Center. Surgical pathology Gleason 7. Stage T3a (positive margin left lateral.)  seminal vesicles invasion absent, regional lymph nodes pNX, extraprostatic extention present on left lateral side.
POST OP: 10 May 2007: First post op PSA was TBD. 

Regular Member

Date Joined Oct 2006
Total Posts : 444
   Posted 4/28/2007 12:53 PM (GMT -6)   
Hi Susan

This is in response to your post below! It is always nice to hear from you and hear you kind words. I don't know what I was in a former life--it couldn't have been good considering my life sentence with PC now!

The world of prostate cancer is moving so rapidly these days with new discoveries and great promise for the future. I am just trying to pass on information that may be useful to members and other readers here in hopes that it will help them and give them an opportunity to discuss some of this information with their doctors.

How is Don doing? Anything new on the many avenues you have been exploring to hopefully help him in his current challenges with PC. You know that I want so bad for something wonderful to happen that may help him to eradicate his cancer. The turn down at Loma Linda broke my heart. I did ask you whether the cancer in the distant nodes could be removed through surgery and you never indicated whether or not you pursued this. God Bless!


Posted 4/27/07 7:54 AM (GMT -5) Quote This PostIgnore Posts From myman.. were a researcher/doctor in a former life, yes?

I wondered where you were and now I know...

You do so much for all of us here, just want you to know it's appreciated.

Hope this finds you well,

68, Biopsy 9/27/06, Stage T1c, PSA 7.1, Gleason 6 [less than 5% in two areas], Gleason 7 (3+4) [less than 20% in third area], negative DRE, bone scan and MRI. Starting proton radiation therapy 2/22/07. Treatments completed 4/18/07.

Forum Administrator

Date Joined Jan 2003
Total Posts : 9799
   Posted 7/7/2008 1:07 PM (GMT -6)   
pcdave - I removed the reprinted articles, which is against forum rules and copyright law. Next time, simply post a link to the articles... which does the same thing but we don't break any laws.

Peter Waite, Founder/Editor - Community, Information, Resources

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