Ken has had three.
He says no pain with any. His doc does do the "numbing" procedure. Ken says it is like one quick pinch that feels like novacaine. Then can "hear, but not really feel" the punches, he says it is like a paper puncher in his mind. But doesn't really hurt, just the sound, anticipation of it.
I only went on his last biopsy with him because it was a couple days after he sprained his ankle skiing and was on crutches. He did the first two on his own, and did fine driving back and forth with them.
But it depends on whether they just numb the prostate (like they did in ken's) or actually put you under with a mild sedative. ken has had a couple colonscopy's too, and, for those, they kinda semi knock out and there is no way he could drive or function for a few hours.
I would ask your doc what he does for "pain" etc. It can range from everything from nothing, to valium, to numbing shot, to IV pain med which can be pretty strong.
PSA: 3.7 (2005: 3.4, 2004: 4.0)
Biopsy: 1/10 cancerous, 5% of one core, right apex.
Da Vinci: April 10, 2007, Denver CO
Path results: 1% of prostate involved. Very small tumors on both right and left apex. Negative margins, negative seminal vessicles, lymph nodes left intact. Gleason upgraded 3+4=7.
1st PSA Results: May 11, 2007 <.01