Biopsy curiosity question

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rek3283
Regular Member


Date Joined Jun 2007
Total Posts : 21
   Posted 6/21/2007 2:19 PM (GMT -7)   
My final biopsy was a "saturation biopsy". 
 
The urologist took 44 samples (I was under general anesthesia, thank god!).  One had a malignancy in it.
 
Has anyone else had a "saturation biopsy" or did my URO just make this up?
REK3283
59 1/2 year old healthcare executive
Nashville, TN
PSA:  7.2;  Gleason:  3+3=6; T1a stage.
Pastimes:  Wife, Yorkies, La Gloria Cubana Serie R #5, Corvettes, F1 racing, ALMS racing, SCCA racing, Bulleit Bourbon, Balvenie and other stuff of lesser consequence.
 


aus
Regular Member


Date Joined Sep 2006
Total Posts : 211
   Posted 6/21/2007 4:05 PM (GMT -7)   
"Satuaration Biopsy" is sometimes used in cases where there's an elevated PSA, PC is highly suspected, and previous biopsies have been negative.
 
Not everyone condones the concept: one or two tiny cancers discovered by satuaration biopsy or repeated biopsies raises the debate about significant or insignificant cancers and watchful waiting which Dr Walsh and Dr Epstein have done considerable research on.
One of the Johns Hopkins articles is available in a newsletter item in the winter 2003 edition on "insignificant cancers" at www.urology.jhu.edu/newsletter 
www.prostate-cancer.org has an item on active surveillance in their Nov 06 newsletter. 
 
Not everyone copes with the approach of active surveillance, which depends on the individual situation, however there are often advantages, even if it is used short term while carefully considering treatment options, and choice of doctor, which should be the prime consideration.
 
John
 
 

Dutch
Regular Member


Date Joined Feb 2007
Total Posts : 400
   Posted 6/21/2007 4:17 PM (GMT -7)   

No, not made up,  my BIL had 40.  Said he was uncomfortable for several weeks, but didn't have any other problems.

Dutch



Diagnosed Feb 2001  (Age 65)  Currently 71
PSA 4.8
Gleason 3 + 3 = 6
T2b
Completed Proton therapy @ Loma Linda - Aug 2001
5yr PSA   0.17
Have had no side effects.

Post Edited (Dutch) : 6/21/2007 9:38:00 PM (GMT-6)


pcdave
Regular Member


Date Joined Oct 2006
Total Posts : 444
   Posted 6/21/2007 5:35 PM (GMT -7)   
hi rek

my 1st and only biopsy was 29 samples which is way above average. it seems that most guys get an average of 12 samples which i think it too few. i never asked my urologist why he took so many samples, but it gave me a greater assurance as to the stage of my PCa. A sedative was injected into my prostate through the rectum wall rectum before the samples were taken. I didn't really feel much of anything when the samples were taken.

Dave
68, 29-core biopsy 9/27/06, PSA 7.1, Stage T1c, Gleason 7 (3+4) [less than 20% in one area],  Gleason 6 [less than 5% in two other areas], negative DRE, bone scan and Endorectal MRI. Completed 39 Proton radiation treatments 2/22/07-4/18/07.
First PSA test to be taken 7/07.


Tamu
Veteran Member


Date Joined Oct 2006
Total Posts : 626
   Posted 6/21/2007 8:18 PM (GMT -7)   
rek,

My biopsy included 10 samples. One of the 10 showed the cancer as read by one pthologist. When I changed urologist and went to a univeristy based medical center their pathologist read the slide as atypical and not cancer. My new urologist then sent the slide to Dr. Jon Epstein at John Hopkins. He told me that if it came back as atypical then he would recommend a saturation biopsy. He came back as confirmed cancer so I never had the saturation biopsy.

Tamu
Diagnosed 7/6/06, 1 of 10 core samples, 40%,Stage T1c, Gleason 3+3
Da Vinci on 11/01/06, Catheter out on 11/13/06
56 Years Old
Post Op Path, Gleason 3+3, Approx. 5% of prostate involved
Prostate Confined, margins clear
Undetectable PSA on 12/18/06
No more pads as of 1/13/07
Began injections in April '07


rek3283
Regular Member


Date Joined Jun 2007
Total Posts : 21
   Posted 6/22/2007 6:54 AM (GMT -7)   

I guess I should have clarified.

I think I was in the active monitoring mode for five years, based on the articles that aus listed.

My PSAs had been increasing at varying speed for five years.  I had previously had four 12 sample biopsies by three different urologists, all were negative.  I was just really tired of going in for a biopsy on an annual basis, only to come up empty while being convinced there had to be a malignancy there somewhere.  Otherwise, the increasing PSAs made no sense.  Of course, we now know that the PSA is not the most reliable test in the world of lab tests.

So, after a total of 92 needle sticks over five years, the malignancy was finally located.

Can anybody top 92? devil

 


REK3283
59 1/2 year old healthcare executive
Nashville, TN
PSA:  7.2;  Gleason:  3+3=6; T1a stage.
Pastimes:  Wife, Yorkies, La Gloria Cubana Serie R #5, Corvettes, F1 racing, ALMS racing, SCCA racing, Bulleit Bourbon, Balvenie and other stuff of lesser consequence.
 

Post Edited (rek3283) : 6/22/2007 8:09:53 AM (GMT-6)


Rick Roma
Regular Member


Date Joined Jun 2007
Total Posts : 37
   Posted 6/27/2007 10:20 AM (GMT -7)   
I would imagine. I just had a regular biopsy that I'm waiting on I have no idea how many samples were taken. When I came out of the sedation my doctor was not there to tell me anything..... so I'm just waiting and hoping.

Richard
There is a special church here nestled deep
in the forest.... a beautiful bell hangs at the very top.... it only stops ringing.  When you come through the forests for your voice takes its place....   Richard

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