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Regular Member

Date Joined Nov 2005
Total Posts : 154
   Posted 7/6/2007 1:13 PM (GMT -6)   

Has anyone here done any genetic tests / counseling to determine if there is a PC link?





Veteran Member

Date Joined Jan 2007
Total Posts : 762
   Posted 7/6/2007 6:43 PM (GMT -6)   

We have a strange situation in our famiily where my husband (youngest son of two sons) had Pca, however his healthy 79 yr old father does not. However his dad had his prostate removed more than 25 years ago for other reasons (TURP op), so I often wonder if my father-in-law, may have developed Pca if he had had kept his prostate which was removed? We do not know at this stage about his only brother (my brother-in-law - 55 yrs), but at thiis point as far as we know, he does not have Pca. If my brother-in-law does develop Pca in the future, for us this may indicate some genetic link (unfortunately). If not, my husband may have been an unlucky "one off" within his immediate family, but we do not know how this situation now impacts on my husband's two sons or the future boys in our family.

We therefore will be recommending some of the prostate health strategies to both our boys for their lifetime (in our country however, I have still not tracked down anything vaguely resembling pommegranate juice!!) as promoting prostate health and awareness for families with a history of Pca is about the only strategy around at the moment, along with earlier PSA testing (and more accurate tests in future), of such men and boys, as far as I know.

I do not think genetic testing for Pca is done at this time, and genetic counselling (if it exists), in our experience, is not even even discussed due to lack of research on younger men and what happens to their boys/families etc. The research may be happening but I am not aware of it. All the medical experts can tell us, is that my husband's older son (29 years), should start PSA testing at 40 years.

So thanks for your question. If there is any sort of genetic testing, we would seek it out in future for our sons (29 yrs and 7 years respectively) but I do not think such testing exists - maybe someone here knows the progress of research in the area? Hopefully someone with more knowledge about it, will respond to your post with any information available.

cheers for now, Lana.
Lana posting for husband CJ (49 years). First PSA 3.5 (Nov 06). Open Radical Prostatectomy on Tuesday 17th April 2007. Gleeson 3 + 4 = 7. Confined to prostate. PSA 0.01 (June 07)

Veteran Member

Date Joined Nov 2006
Total Posts : 883
   Posted 7/6/2007 9:14 PM (GMT -6)   

    I would have any male realtives start getting checked at 40 not matter what.  In my case my Grandfather had PCa but not sure at what age.  My father at 69 is clear so far.  So is my brother that is two years older than me.  Go figure how I was the one to get it first.  Could be partly due to where I work and the hazards associated with it.


    PSA 5.7 - Discovered during Annual Physical with Family Practice Dr.
    Gleason 7
    Biopsy - 3 of 12 positive (up to 75%) all on left side of prostate
    RRP on Oct. 17, 2006 - Nerves on right side saved.
    All Lab's clear.  No Cancer outside prostate
    Cathiter in for 3 weeks due to complications in healing. Removed Nov. 9, 2006
    First Post op PSA on Dec. 11, 2006  Undetectable 0.00
    Office visit on Jan. 19th due to continued excessive urine leakage.
    Feb.20th Cystoscope and 2nd Post Op PSA. Another 0.00.....:)
    Dr. said everything looks fine.  Continue to work Kegeal's. Leaking appears to have improved  after Cystoscope?!?!?!  Down to 3-4 pads per day!
    March 1st  Leaking has crept back up to 6 - 8 pads a day ??????? 
    March 8th Started Detrol LA to see if it helps with the leaking?
    March 29th Collagen injection into sphincter / bladder neck area to control excessive leaking.  Worked for a couple of days then back to leaking.
    April 17th (Six Months Post Op) 2nd Collagen Injection to control excessive leaking.  Leaking started back next day at work!
    May 14th Second Opinion about my leaking and Options at OU Medical Center.  After reviewing my records the Dr. feels I will probably need some surgical intervention to stop my leaking.  But did agree to try Bio-Feedback and work hard on the Kegeal's first!
    May 30th Follow up with my Dr. and 3rd Post Op PSA 0.00 agian!!!
    June 1st Start Bio-Feedback to try to control my leaking.

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