Question about my dad

Hi Everyone,

 

I need your opinion about my father.  He is 75 years of age. His Urologist recently performed a DRE and said that it didn't feel right and that my dad needs a biopsy.  My father has an enlarged prostate (I don't know the size but I was told that it's very large) and he's been on Proscar for the last 8 years.  His psa level is 4.0 and has been pretty much stable with the exception of several years ago it jumped to a 16 and then slowly went back down to 4.  The Urologist said it was probably an inflammation of some sort and didn’t do a biopsy.

 

My dad went for a second opinion to a very well known Urologist in Manhattan.  He examined my father and said that he did feel something during the DRE but thinks it could be an inflammation.  His advice was not to do a biopsy for now and see if the psa goes up within the next 6 months.  He also said that since his prostate is so large that he wouldn’t be a candidate for seeds or radiation. 

 

What do you think of this wait and see approach at this point?  What do you think my dad should do at this time?

 

Thank you.

 

AEG

 

I just wanted to add that Proscar can artificially lower the psa by 50%.

AEG

Hi AEG,
Since you asked, here's my $0.02 worth. If they were asking him to perform surgery, I'd say by all means wait. But the biopsy is not that big a deal, and should give him an affirmative answer. I never showed any symptoms of PCa, and my tumor was not palpable right up to surgery. I personally would go crazy waiting and wondering: Will my PSA go up? Is the cancer there and growing? Was that really something he felt during the DRE? Am I decreasing my survival odds by waiting? All of these things would whirl in my mind 24/7. It's never an easy decision. Whatever you decide, I'm thinking of you and you Dad.
Best,
Mike

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June 2005 - Age 53 PSA 4.8 at regular physical
October 2005 - After several rounds of anti-biotics, PSA 5.2 at Urlogist
November 2005 - Biopsy negative
July 2006 - PSA 5.9 at regular Physical
October 2006 - After several more rounds of anti-biotics PSA 8.1
November 2006 - Second biopsy - Positive
December 2006 - Gleason (3+4=7), Tumor T1c, CT Scan and Bone Scan Negative
January 2, 2007 Robotic Prostatectomy, University of Rochester Medical Center - Tumor confined but larger than thought, only one nerve able to be spared. Margins clear.
February 2007 - Three to four pads a day, no erection with viagara.
March 2007 - Down to two pads a day, had first intercourse with Erecaid pump and bands, otherwise still flat tire.
April 2007 - First Post-Surgical PSA 0.02 and a great relief! Down to one pad a day. Still unable to achive erection without pump.
May, 2007 - Still one pad a day, even try a smaller pad on occasion. Slight improvement on the ED.
July, 2007 - Six Month Post-op: PSA 0.04 still Non-Detectable. One small pad/day for a few drops only! No change in ED.
"If patience is a virtue, I feel like the most virtuous guy on the planet!"

hi,

yeah I would agree that doing a biopsy would be minimally invasive.

unless he has some health condition or something that is making them hesitant to do that?

and from our experience, your PSA score does need to be multiplied by a factor from being on proscar or avodart.  But, we were on avodart for only about 4 months after diagnosis but pre-surgery.  And it went down from 3.7 to 1.9.  (but doc multiplied it to about 3.4).

I am not sure though if being on it as long as your dad and having pretty stable PSA's would mean it has stabilized?  But anyway, is there any disadvantage in his case in getting a biopsy?

Tanya

 

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Age: 63
Diagnosed: 10/30/06
PSA: 3.7 (2005: 3.4, 2004: 4.0)
Biopsy: 1/10 cancerous, 5% of one core, right apex.
Gleason: 3+3=6
Da Vinci: April 10, 2007, Denver CO
Path results: 1% of prostate involved. Very small tumors on both right and left apex. Negative margins, negative seminal vessicles, lymph nodes left intact. Gleason upgraded 3+4=7.

1st PSA Results: May 11, 2007 <.01