I believe all prostate cancer is very insidious and risky. But I was not shocked after a biopsy Gleason 10 put me in a high risk
catagory. I was immediately put on hormone therapy (PSA only 5.7) and scheduled for surgery on 2/14/06. The path findings revealed a Gleason 5 + 4 = 9 and seminal vesicle involvement.
The cancer had grown out of the prostatic capsule. I've had 2 bone scans which were clear. Next came adjuvant radiation therapy, June thru July of 06. My PSA as of May 29th is a very negligible .01. Everything appears to be going fine.
Now my uro wants to take me off hormone therapy despite high risk features. I've been on hormone therapy or intermittent HT since 12/03/05. You'd think I'd be glad to get off this form of therapy. It prevents testosterone production which presents a list of nasty side effects including: loss of libido, muscle mass reduction, fatigue, thinking problems, weight gain, and possible anemia. But high risk prostate cancer can feed off testoterone causing a recurrence.
I know it is not unusual for uros to discontinue hormone therapy after about 2 years. I want testosterone production as much as any man. It would alleviate the side effects I mentioned. I just don't know if it's safe or if it has become a very uncomfortable security blanket.
I know men who have been on hormone therapy for 3 or 4 years without a recurrence. Are they wrong? I realize that everyone is an individual who has to make his own decisions. This is a tough one. I have gotten mixed second and third opinions. Most agree, despite positive attitude, that this cancer will most likely come back within 1 to 5 years. It's like a crap shoot.
Would you take the risk of stopping hormone therapy to feel like your old self again knowing that a recurrence while on hormone therapy is still very possible? Or realize that it can stop cancer recurrence for many more years?
I don't expect a definitive answer. I'm not sure what I expect from you. Maybe just writing about the decision I have to make is helpful in some ways. Prostate cancer can be a mean old nasty dog that bites you when you least expect it. I do or don't get my next 3-month hormone shot in August. Not sure what to do.
Biopsy: Gleason 10
Hormone Therapy: 12/15/05
EBRT: 6/05/06 thru 7/25/06
Diagnosis: T3b Seminal Vesicle Involvement, Gleason 9
Current PSA: .01
Post Edited (veteran1) : 7/24/2007 9:00:17 AM (GMT-6)