post surgery psa (corrected PSA 0.28)

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Regular Member

Date Joined Feb 2007
Total Posts : 122
   Posted 8/6/2007 4:08 PM (GMT -6)   

My first post surgery PSA is 0.28 and my Dr recommends I have radiation my pre surgery psa was 5.8 gleason 3+4 anyone else in this boat? any suggestions?

50 years old

gleason 3+4=7 psa5.8 clinical stageT2a

Da vinci surgery April10 2007 Mayo clinic Rochester, Mn.

extraprostatic extension Gleason -same

pelvic lymph nodes -negative

Catheter out April 19



v      bluebird ~  Moderator for Prostate Cancer Forum

helped to show correct PSA 0.28 per new thread showing correction

Post Edited By Moderator (bluebird) : 10/6/2007 9:47:15 PM (GMT-6)

New Member

Date Joined Aug 2007
Total Posts : 9
   Posted 8/6/2007 11:40 PM (GMT -6)   
Yes, I had a similar diagnosis and treatment. At age 52 I was diagnosed, Gleason 3+4, with a PSA of 6.2. I had an RP, and 14 months later my PSA went from 0.1 after the surgery to 0.6. I immediately had radiation, and my PSA dropped to between 0 and 0.2 and my doctor says I'm in remission. I was diagnosed 9/11/01, RP on 1/02 and radiation in 3/03. I've been in remission since then, but still take supplements just in case.

Regular Member

Date Joined Sep 2006
Total Posts : 187
   Posted 8/8/2007 9:41 AM (GMT -6)   
My PSA went up to .24 about five months after surgurey---- but I also had a positive margin, which was highly suggestive of residual disease.    .2 was the line in the sand I had agreed upon to do radiation.    I did 36 sessions of IMRT and six months worth of Zoladex.  Last PSA undectable, but that's under HT --- time will tell.
IMHO, your doc is giving you good guidance.
Age 47
Initial PSA march of 2006: 28
PSA May of 2006: 39
8 of 12 cores malignant
Open Radical Prostatectomy 6/9/2006
Pathological Stage T3a, Positive Surgical Margin
Gleason 3+4
Post surgury PSA fluctuated between .04 and .09
PSA rose to .24 in November of 2006
6 month hormone therapy initiated December 1. 2006
36 sessions of IMRT Ended Feb 1, 2007
PSA as of May 25, 2007 undetectable
Next PSA November, 2007

Regular Member

Date Joined Apr 2007
Total Posts : 101
   Posted 8/8/2007 12:28 PM (GMT -6)   
Kinda sort psa 6 weeks after surgery was 0.62 but my doc said he wasn't surprised concerning my post surgery pathology...gleason upped to 9 and positive margin and seminal vesicle involved....had another psa a couple weeks later and had dropped to 0.59...started lupron therapy, due for another psa in late
September and begin radiation treatment just after Labor day....hoping for close to zero on next psa...
age: 61
PSA 4.57 - Positive DRE
Biopsy 3-19-07 - Gleason 4+4=8
Negative bone scan 3-20-07
DaVinci 4-24-07
Catheter out 5-01-07
post op pathology:
positive margin left side of prostate
left seminal vesicle involved (both removed)
No lymph node involvement
New gleason score 9
T3B....radiation consult on 5-9-07.

Tony Crispino
Veteran Member

Date Joined Dec 2006
Total Posts : 8128
   Posted 8/8/2007 2:07 PM (GMT -6)   
Being Lucky I guess. My post surgery (2/16) pathology was 4+3, pT3b (yup on the seminals). PSA was undetectable when I started HT 3 months later. Started IMRT for 38 hits and completed 8/3 with still a <0.1. Next PSA in September.


New Member

Date Joined Aug 2007
Total Posts : 1
   Posted 8/17/2007 11:35 PM (GMT -6)   
My 4 week post-op PSA was 0.51 and this week my 3 month (almost) PSA was 0.28. Doc says below .3 and steady is OK. That's the $10 million question. He scheduled the next one for November. Should I talk to an oncologist ion the meantime?

Tony Crispino
Veteran Member

Date Joined Dec 2006
Total Posts : 8128
   Posted 8/18/2007 12:20 AM (GMT -6)   
Uh, Yea!
Absolutely confer with a second opinion at any point you can with cancer. You sound like you are doing well but you have to be vigilent.

Age 45 (44 when Dx)
Pre-op PSA was 19.8
Surgery on Feb 16, 2007
Post-Op Pathology was poor: Gleason 4+3=7, 4 positive margins, Stage pT3b (Stage III)
HT began in May, '07 with Lupron and Casodex 50mg
IMRT radiation for 38 Treatments ending August 3, '07
My PSA did drop out after surgery to undetectable.  It has not returned and I will continue HT until January '08.
My Life is supported very well by family and friends like you all.

Veteran Member

Date Joined Aug 2007
Total Posts : 1015
   Posted 8/18/2007 12:46 AM (GMT -6)   
Hi Mickeypro,

Tony is the voice of experience.

Since you're not where you want to be with the PSA after 3 months (PSA < 0.20), getting another opinion, and perhaps another test, could be in order.

As Tony inferred, you want to stay ahead of the game.

Age: 54
PSA: 4.3
Biopsy: T1c, 3+3=6, 2 pos. samples in one side of prostate, <5% volume
Da Vinci 31 Jul 2007: saved nerve bundle on side of non-cancerous side
Final pathology: Confined to prostate, T2a, 3+3=6, <1% volume
Working to get back into good shape
Waiting to take that first post-op PSA

Regular Member

Date Joined Jan 2007
Total Posts : 165
   Posted 8/19/2007 12:54 PM (GMT -6)   

Hey Mickeypro

As you can see by my signature line, many of us are in the same boat.  While I had only a .08 at the 5 month mark, my surgeon and oncologist were discussing the possibility of adjuvant radiation therapy when it was .01 at two months.  I've been on Zoladex for two months now, and am scheduled to start 32 radiation treatments the last week of this month.  I've been keeping physically active and don't feel the fatigue effects of HT.  I don't know what a hot flash would feel like, but at times I do feel pretty warm, but it's Summer.  My doctors, and some studies, indicate that the HT will help weaken any cancer cells that may be in the prostate bed, so the radiation can be more effective.  I have always approached this aggressively, and will continue to do that.  Hang in there....

PSA 4.7 (up from 3.2 one year ago)
Biopsy November 8, 2006 1 of 10 cores positive 5% LEFT Side Gleason 3+3
Robotic surgery January 19, 2007
Post Surgery Pathology
     Stage T3a, Gleason 3+4, positive margins and
     capsular penetration RIGHT Side
Post Surgery PSA:  March 5:  0.01
5 month PSA, June 13, 2007:  0.08
Adjuvant therapy began June 26 with Zoladex injection
     Radiation to commence in late August

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