radiation pros/cons

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Regular Member

Date Joined Feb 2007
Total Posts : 122
   Posted 8/7/2007 6:02 AM (GMT -6)   
What are the pros and cons of the radiation therapy, are there dos and don'ts while having the teatments? what can I expect. worried
50 years old
gleason 3+4=7 psa5.8 clinical stageT2a
Da vinci surgery April10 2007 Mayo clinic Rochester, Mn.
extraprostatic extension Gleason -same
pelvic lymph nodes -negative
Catheter out April 19

Tony Crispino
Veteran Member

Date Joined Dec 2006
Total Posts : 8128
   Posted 8/7/2007 9:03 AM (GMT -6)   
Hi mgl,
You are following my path. I completed my surgery on 2/16. I then commenced on hormone therapy. I completed IMRT radiation just last Friday. If you are considering hormone therapy, I would start it then move on radiation three weeks later or so. The logic, so I'm told, is that the HT begins to shrink any extra-prostatic extension while hitting it with radiation. MY RO did not recommend this but he did indicate that there is logic in this method. I had 38 IMRT sessions. I feel great and only had a brief looseness in my bowel movements. I am still undetectable and am hoping that radiation will keep it that way. With a Gleason 7 and I believe you are pT3a post operative stage? Then I would proceed with radiation. Don't worry though. You will likely fair well and certainly feel better that you are taking action. Mayo is a great institution and I am certain that they did a great job surgically. I like you have Stage III disease and feel better knowing I took the right action. Side effects have been minimal for me.


New Member

Date Joined Aug 2007
Total Posts : 9
   Posted 8/7/2007 10:19 AM (GMT -6)   
I had IMRT and I had radiation cystitis 2 years later, which was cured with hyperbaric oxygen. Other than that, I had no problems. It saved my life.

Regular Member

Date Joined Jan 2007
Total Posts : 165
   Posted 8/7/2007 11:24 AM (GMT -6)   
My surgeon and radiologist had me go on Zoladex two months prior to commencing my radiation, which will begin the end of this month.  As TC mentioned, the studies indicate that the HT will weaken the cancer cells, so the radiation will be more effective.  How long I will be on the hormones is another issue.  My surgeon feels two years, while I've read that only 6 months are necessary.  I guess we'll wait until the radiation is done to make this decision.  So far, I've not had a problem tolerating the Zoladex.  I still take my one hour walks in the morning and have continued my sports officiating with no problems.
PSA 4.7 (up from 3.2 one year ago)
Biopsy November 8, 2006 1 of 10 cores positive 5% LEFT Side Gleason 3+3
Robotic surgery January 19, 2007
Post Surgery Pathology
     Stage T3a, Gleason 3+4, positive margins and
     capsular penetration RIGHT Side
Post Surgery PSA:  March 5:  0.01
5 month PSA, June 13, 2007:  0.08
Adjuvant therapy began June 26 with Zoladex injection
     Radiation to commence in late August

Tony Crispino
Veteran Member

Date Joined Dec 2006
Total Posts : 8128
   Posted 8/7/2007 11:57 AM (GMT -6)   
MGL and Hawk,
Stay close as we have much to share. For me it was Lupron but same difference. It was 1 month for me on the lapse after starting HT until IMRT. Not sure as which is better but it does lend credence to the idea and it seems our doctors agree. My medical oncologist is indicating an intermittent HT and will be providing me one more injection next month. I will continue the Casodex until end of January and will stop both treatments. I will likely start taking Proscar or Avodart thereafter. This is following protocol in the Myers book. I recommend that book to all stage III or IV patients here as it is written with us specifically in mind. Good luck to you both and see you here again soon. I have enabled my EM adress here and feel free to ask any questions.

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