I spoke to a research pathologist, and he did a DNA analysis of 7 positive cores in a prostate, and found all 7 had a different DNA. That means that in this case we're fight 7 different cancers, not just one. Boy does that throw a monkey wrench into the treatment (Provenge won't work, for example). These cancers could be anything form non-invading, to very aggressive. That could explain why some people don't do well with treatment, and others do extremely well.