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Veteran Member

Date Joined Jun 2007
Total Posts : 789
   Posted 8/16/2007 7:21 PM (GMT -6)   
Hi everyone, just wondering what the more experienced members think about my post-op pathology, read some where that even one microscopic cell can regrow, see Uro next week, maybe I am reading too much ?
Regards Mal. :-)
age 66 PSA 5.8 DRE slightly firm Rt
Biopsy 2nd July 07 5 out of 12 positive
Gleason 3+4=7  right side tumour adenocarcinoma stage T2a
RP on 30th July,
Post op Pathology, tumour stage T3a 4+3=7, microcsopic evidence of capsular penetration, seminal vessels, bladder neck, free of tumour, lymph nodes clear, no evidence of metastatic malignancy, tumour does not extend to the apical margins.

Regular Member

Date Joined Apr 2007
Total Posts : 101
   Posted 8/16/2007 7:36 PM (GMT -6)   
Maldugs.....I would love to have your post op pathology......I'm sure that one microscopic cell could definitely grow and again cause problems....however hopefully with regular psa testing you would have a handle on it if something did pop up. Your pathology isn't the best I've seen on this site but just look around and thank your lucky stars. Good luck in your walk....regards jwb.
age: 61
PSA 4.57 - Positive DRE
Biopsy 3-19-07 - Gleason 4+4=8
Negative bone scan 3-20-07
DaVinci 4-24-07
Catheter out 5-01-07
post op pathology:
positive margin left side of prostate
left seminal vesicle involved (both removed)
No lymph node involvement
New gleason score 9
T3B....radiation consult on 5-9-07.
June 5, 2007 1st psa post surgery 0.62
June 19, 2007 second psa post surgery 0.59
June 19, 2007 started Lupron injection (24 mos)
September 6, 2007 scheduled to begin radiation treatments

Veteran Member

Date Joined May 2006
Total Posts : 2542
   Posted 8/16/2007 9:48 PM (GMT -6)   
Hey ~ Mal,
Thought this might be of interest...

**Excerpts taken from “Dr. Patrick Walsh’s Guide to Surviving Prostate Cancer”

by: Patrick C. Walsh, M.D. (Professor of Urology, The Johns Hopkins Medical Institutions)

     and Janet Farrar Worthington.   Copyright 2001

  Page 145


**What about Perineural Invasion? 

As cancers grow, they compress normal tissue, looking for “elbow room”—spaces with less resistance, where they can spread.  Nerves are usually surrounded by some empty space; for cancer, this is the real estate equivalent of a nice suburban lot with a big backyard—plenty of elbow room.  Thus, it’s not uncommon to find prostate cancer in the spaces around the nerves; this is called ‘perineural invasion.”  Because the nerves are most common close to the surface of the prostate, the findings of perineural invasion on a biopsy suggests that the cancer is close to the edge of the prostate, and may well have penetrated the capsule.  However—this is important to keep in mind—cancer that has penetrated the capsule can still be cured.  Which makes this a paradoxical finding—because, although men with perineural invasion are more likely to have capsular penetration than men without it, perineural invasion has no long-term impact on whether or not a man can be cured.  For this reason, some noted pathologists have suggested that it should not even be commented on when found in a biopsy, because it’s not worth worrying about.

mama bluebird - Lee & Buddy… from North Carolina


v          We invite you to visit our personal thread:  Click Here:  “Our Journey” ~ Sharing is Caring 

April 3, 2006  53 on surgery day

RRP / Radical Retropubic Prostatectomy

PSA 4.6   Gleason  3+3=6    T2a   Confined to Prostate

3rd PSA 08-07-2007 Less than 0.1 Non-Detectable :)

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