PSA Doubling Time ?

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New Member

Date Joined Oct 2007
Total Posts : 1
   Posted 10/2/2007 4:50 PM (GMT -6)   
I am new to this forum but feel so lucky to have found it. My husband just received the dx last week after a biopsy. Today we found out that in 2006 his PSA was 1.7 and now it is 4.2. They found one spot that was a gleason 7.
We have not had a meeting with the urologist --we got the information by phone. They will hav a meeting when the results of all the tests are in.
He had a bone scan today and will have a cat scan this week.
I have already asked to have the pathology report and slides sent to Mt. Sinai in NYC where there is a Dr. Sedami who does the robotic surgery. I read about him on this site. We are not sure what will happen or if he is even a candidate but trying to stay ahead of the curve.
Specific question is about the doubling? Obviously this is a big jump in 18 months. Can anyone expalin this? I did the calculations but think I am so upset that I am unable to understand it. 
Thank-you to all on this site for the support and concern that is so evident.    

Veteran Member

Date Joined May 2006
Total Posts : 2542
   Posted 10/2/2007 7:07 PM (GMT -6)   

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Cedar Chopper
Regular Member

Date Joined Mar 2007
Total Posts : 432
   Posted 10/3/2007 5:42 AM (GMT -6)   

While doubling time can be a helpful measure,
my understanding is that the biopsy 7 gleeson is a much clearer
  (not all inclusive until a post prostatectomy biopsy)
   a much clearer measure of what is going on.

I applaud your deliberate approach and sending the slides to Mt. Sinai without delay.
A "7" would cause me to move quickly -
   -to whatever treatment option I decided upon.

While logged on, in the upper left corner of this page you will find the "Control Panel."
You can customize a "signature" there that will let us know things like your husband's age,
gleeson score, etc.  This will improve the responses to your questions.

You have found friends here!



2 Years of PSA between 4 and 5.5  + Biopsy 23DEC06 
Only 5 percent cancer in one of 8 samples.  +  Gleeson 3+3=6
Radical Prostatectomy 16FEB07 at age 54.
1+" tumor - touching inside edge of gland.  + Confined:)
Pad Free @ 14 weeks.  Six Month PSA <.003  :)
At 6 months, ED treated with Pump Exercises & 50mg Viagra Daily
Texas Hill Country FRESH Produce Department Manager
Have you had your 5 colors today?

Regular Member

Date Joined Jun 2007
Total Posts : 176
   Posted 10/3/2007 7:20 AM (GMT -6)   
good news is that his PSA is still relatively low and gleason 7 --whether 3+4 or 4+3 -- is still a moderately agressive cancer. 3+4 is typically said to be close to 3+3 and therefore not as agressive as 4+3 which is closer to a 4+4 and categorized with more aggressive cancer. either way, treatment will be recommended and likely surgery. do you homework though. there are numerous options for both surgery (open/DaVinci) and radiation (Proton Therapy, Brachyatherapy-see implants, IMRT, etc.). each has pros and cons and each needs to be evaluated relative to your specific situation. be proactive, but take the time you require to make the right decision for the two of you.

and talk to people and ask them about their experience with treatment. you will find that EVERYONE will be willing to talk to you. this site is a great place to meet people with prostate cancer, but you will also find that many people you know will know someone. i talked to many people before choosing my treatment option.

know that you are not alone in your concerns, fears and hopes for beating this. and you'll find much encouragement along the way.

42 yo.
PSA 4.65
Gleason scores from 4 pathologies of the same biopsy with 2 of 12 cores positive for cancer (if this isn't confusing to the patient...):
1) both cores 3+4 (Weiss Memorial)
2) one 3+4 and one 3+3 (Univ. of Chicago Hosp.)
3) both cores 3+3 (Mass General Hosp.)
4) both cores 3+4 (Northwestern Memorial Hosp.)
9/17/07 - Radical Retropubic Prostatectomy Surgery at Northwestern Memorial in Chicago by Dr. William Catalona.
and the winner op Gleason score of 3+4.
Good pathology report with negative margins, no seminal vesicale involvement, no lymphatic or vascular invasion, bladder and urethral free and tumor volume was 5% of 27.3g.  Amazing how something so small can cause such problems!
9/27/07 - Catheter removal...let the games begin...

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