Injections started today

Promised I would post after my appointment today re: injection therapy. The whole process went very well. The doctor explained what the medicine was (Tri-mix) how it works and how to do the injection. Then we did the first one together. Must admit that the needle looked very BIG but was a mere prick and took only a few seconds. The results were fast and very , very good, I'd say 75%. The amount I used was fairly low as this was just a teaching situation. My Dr. said with a little more med. and some stimulation I'dd have what I have been waiting for for 5 mos., I nice hard erection. Yippee. The compounding pharmacy is to get the meds to me in the next week or so, I have been instructed to use it at least three times a week (yippee)  until I get the doosage correct. For those of you on the fence about injuctions, I heartely advise you to give them a go.

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Diagnosed 1/26/07

Good deal, Pete.  We discusssed this issue today and Doc said he prescribes Viagra 25mg, and after a couple months or so I had no response, then he would prescribe a pump.  I told him I was willing to try the pump if he wished , but that if left to me, I would go straight to the injections both for function and therepy.  He didn't seem adverse to the idea and asked me if I had done a lot of research about it.  I told him I had, and felt this might be a better thing for me.  He said he would be interested in following up closely with the results if we did go this route, that maybe this is another viable alternative.  He is a younger Doc. who works daily with a older Doc who is much more experienced in general Urology terms and I suspect he tends to follow his lead.  He told me that other Doc had begun prescribing the pump to his patients 6 months ago for penile lenghtening and erections, using it in the shower to keep an erection the length of the shower and he had begun doing the same, based on the other guys patient results.  This guy is a wonderful doctor and surgeon, with no ego and seems willing to let the patient participate in their treatment plan and is adaptable to new ideas that my not be his.  All in all, I feel I got the best Doc and the best procedure in town.   lol Anyway, I wander off course now, but will be interested in your progress with the injections.  It still seems the best option for us, once the aversion to the physical process is overcome.  lol

Way to go Pete! Keep us posted.
Curt

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Age 52
Diagnosed 2/19/07
10 of 24 cores positive
Gleason 3+3=6 Changed to Gleason 3+4=7 after surgical pathology
PSA:3.3
DaVinci Prostatectomy May 11, 2007 at Univ. of Mich. Hospital
Stage: T2b
Pathology: May 16 - Cancer confined to prostate, Margins, Lymph & Seminal Vesicles all CLEAR!
Father and Uncle had prostate cancer
First PSA after surgery- July 5, 2007 = <0.01 !!!!!!!

Pete,

Do you remember the dosage he has prescribed?  .10cc? .20cc? .30cc?

Gene

Starting with .05 and incremental increases of .o5 after that. He also said that some of his patients also have good results using in combination with 50 viagra, that it was up to me to find out what works best for me. He is definately of the opinion that early injection therapy helps in bringing about spontaneous erections more quickly to those of us that seem to have a little trouble in the beginning.

Hello!  Also new to Tri-Mix at a recommended dosage of 0.2cc to start next Monday.

The first trial injection was for 0.1cc and in 20 minutes I was about 50% erect for about 45 minutes.  This was unbelievable after 10 months in adition to trying five other unsuccesful methods.  I am anxious as a little kid. 

Based on experience, can anyone tell me if the erection will persists after climax?  I have had Robotic RP 10 months ago with very limited success along the way.  I'm a little down but have not given up.  But the idea of an erection after climax seems outstanding.

Thanks, Geon

 

Geon - In our case the erection lasts about 2 hours total . . . so yes after climax as well.

;o) Linda & Bob

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Bob (61) - Laproscopic Prostate Removal Sept 27, 2006.

Geon,

As lawink says the erection does last after climax. My experience is the same with it lasting about 2 hours. Higher dosages that I tried until settling on my present level of .20 cc's of Bimix made the erection last longer but did not give me any more firmness. What you have to realize is that the erection will become firmer with stimulation so the 50% you got in the office may hav been a lot more at home.

Tamu

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Diagnosed 7/6/06, 1 of 10 core samples, 40%,Stage T1c, Gleason 3+3

Geon,

I am new to injections too.  I have had four now and finally got dosage and tecnique right, I think.  The first three were not very successful, but # 4 was very successful.

The doc first prescribed .10cc (& I used that dosage for the first three times and now he has uped it to .20cc.  I used just a little under the .20 for # 4 (which was by far the best of the 4).  Erection lasted 2 hours, but I don't want it lasting longer than I need it.  I don't care to keep on and on like the bunny.  When we are finished, we are finished till the next time. 

The remaining time after orgasm was a little painful because I could not get it tucked in a comfortable position.  It would not bend downward comfortably 'cause my jockeys pulled up on it and sort of jammed it and I could not tuck it upward because it created pain at the base.  I will take the two hours over nothing, but one hour or less is fine.  Plus, I sure don't want an ER situation. 

Each of us are different, as I have been told on this forum so many times by these friends.  But after ten months you might not want to keep using that erection until it goes down.  The stimulation might... just might make it stay up and up and up until it is, "Hello, Nurse Smith.  Yes, it's good to see you again too.  Yes, the family is just fine, but... Help.  I've gotten up and I can't get down." 

Gene 

A very special thank you to all.

Thank you Linda, Bob, Gene6163 and all for your openess and  honesty.  You give much comfort.

Thank you also Pete42, James C., CVK, Tamu and all.  Most reasuring.  What agrand feeling to know that someone else is in the same boat.  Hope I can be of some support to you in the coming months.

Geon

Quote from above….Pete42 said...

Pete,

Great for the erection even if it was 75%! As a male it is unexplainable and feels so leavening.  Like you died and went to heaven I guess.  What a heavenly feeling!  I totaly understand.  After 10 months, I am praying that a hard erection will come to me as well as you in the near future.

I'll keep you poted and hope to hear from you also.

Geon

No Geon, you are not out of reason.  If I understand the injection medications, you will have suitable erections with it when you learn how to inject yourself properly with the proper dosage.  Just be careful when you give yourself the injections.  Concentrate on what you are doing and where you are sticking the needle.  It is somewhat frightening to do that.  I've done it four times now and am still a little shakey, but each time I do it I am a little more calm (You are right Tamu).  Read the pamplets and diagrams regarding injections very carefully. Then read it all again and again.  I ended up injecting too high on one of the four times and there was no reaction to the meds... none.  The last one was a big 8 (on a scale of 1-10).  Sex will never bea exactly as it was before the surgery, or so most guys who've had this surgery say.  It is different but that difference ain't half bad!  As a matter of fact, it's pretty good. Maybe not as good as before, but pretty good just the same.

I know what you mean by not feeling alone.  I have been horified that someone would recognize me from my posts but I am at the point now that that is of little concern.  I still don't want people knowing my real name (Thank you HW for the confidentiality of this forum), but the people on this forum have gone through exactly the same things and sympathize.  We should help one another out with our personal experiences.  I know people here have really helped me. 

Take your time and enjoy the wife God has given you.  It will happen.  Be patient.  You share some of the same motivations for wanting to function sexually as I have:  A love and concern for your wife even more than for self.  It's not just sex to feel good personally.  It is sex to share with your life companion.  When one has that motivation, the feel good part we experience is good and blessed.  Our Creator meant for husbands and wives to please and fulfill needs of one another in the realm of their committed marriage relationships.

Gene 

Gene6163,
Thanks for the heads-up (pardon the pun). This after noon I took on the courage to inject myself for the first time. The time appeared to be right. I was relaxed, warm, comfortable and mentally prepared to do the deed. Last night my wife and I did release our tensions after a difficult day (fall festival) unfortunately without an erection. The orgasm was almost non existant but noteciable. Anyway, the injection was for practice and penile excersize at the suggested dose on 0.05 (less then 0.1 in the office). Well by the time I got to injection the fluid amount was about 0.08. 20 minutes later I was 60% erect and getting tighter. What a wonderful feeling after 10 months. The feeling was nothing like the VED. This was natural as I can remember - wow or Yipppee like Pete said. With manual stimulation the penis actually engorged more but still hanging downward some and not horizontal nor up. But this is Ok, it's a trial run and I was so proud that I went in to the computer room to show my wife as she was playing games on the computer. She stopped playing computer, touched me and said that this is the hardest I have been since before DRP surgery. I also was given a couple of pumps by her for encouragement.

This erecetion lasted 1 hour 20 minutes where I could have had vaginal penetration. With minor stimulation about 80% of that erection remained for another 25 minutes. I must be close on the dosage and it is not near what the PA told me to try at 0.2. You are correct, after 10 months, I will probably not have what it takes to wear down 1 1/2 of erection so I plan to inject about 0.12 or so in a couple of days. The erect penis with trimix seems so much more sensitive with the nerve endings exposed I guess that some stimulation goes a long way. I was just like a teenager...... No orgasm today as I had satisfaction with a simple erection but I also did not feel the need to orgasm. The urge just was not there. When I proceed with penetration I suspect (hope) this will change.

The injection went well with very little pain (like none) and insert feeling. In it went and up she came.

Hope this helps some of you and again, thanks to all. Wish I could talk openly this way generally but I think I would be locked up. Thanks for the privacy. Replies appreciated. You make me feel comfortable and wanted. You all are in my prayers also!

PS. I'll keep you posted on my first intercourse attempt in a couple of days.
Geon

geon,

Congratulations!! Your plan for increasing the dosage is reasonable. Remember to alternate sides.

Enjoy!!

Tamu

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Diagnosed 7/6/06, 1 of 10 core samples, 40%,Stage T1c, Gleason 3+3

Tamu,
Thank you so much.
I'm working on my profile as time permits and will submit soon.
Thanks all for your support.
Geon

In response to the question of whether the erection continues after climax with injections, it has been my experience that the erection actually gets firmer after the first orgasm. I have experienced the same phenomenon to a lesser extent with Viagra. Has anyone else had this experience? I get a little concerned that if I keep going, I may have difficulty losing the erection. It takes a while to get used to chemically induced erections and this still seems to be a strange new world.

Last night was my first attempt to intercourse for over 10 months abstanence.  First trimix (0.1) in the doctors office, second at home (0.08) and third last night at 0.20 as recommended by the PA woman.  My full erection was attained within 20 minutes as expected.  Tenderness set in with burning and ache pain.  I climaxed about one hour after the firm erection with much discomfort.  As a result I could not go on with any more ativity as I much desired to aspecially after a 10 month wait.  As I lay there, the erection is getting more firm with greater discomfort.  After 1-1/2 hours I get to be a little concern.  After 2-1/2 hours I call the doctors exchange, they get the doctor asleep an I attempt to discuss my issue.  The doc tells me to ********* and it should go away.  In a void of comment following, I ask doc what about a cold pack and sudafed.  He respondes, ya that might help.  Before hanging up he tells me that I was good with an erection for up to six hours....end of conversation.   Great, I am beginning to panic and decide to try ********** to my dislike and this was impossible after about 8 to 10 minutes.  My penis was so sore it did not need to be touched...as you can understand, I was not in the mood.

geon,

Your plan was to go to 0.12 cc's. The jump from .08 to .20 is a large increase and I am surprised that the PA suggested it. You have to factor in the increase in the erection from stimulation. I found that I did have some aching for the first four or five times and then it went away. As already mentioned it will also become firmer when you climax. Trimix also has some Alprostadil in it which can cause aching. This is the medication that is in Caverjet. Alprostadil gave me significant aching and I could not use it. My urologist switched me from Caverjet to Bimix which has no Alprostadil in it. If you still have aching at the lower dosages ask to try Bimix.

Tamu

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Diagnosed 7/6/06, 1 of 10 core samples, 40%,Stage T1c, Gleason 3+3

Penile injections do take some esperimentation in order to find the right dose. I take 50 mg Viagra before dinner then .05 ml Trimix injection a few hours later. This gives a very satisfactory erection that lasts for about an hour. I had some pain when first using Trimix and found that the less I use the better the feeling and the less pain. After experimenting for about 2 months with various doses of Trimix and Viagra, this combination and timing works best for me.

My uro started me with .10 ml Trimix and it was way too much. I had a 5 1/2 hour erection that was very painful. So I cut down to .02 ml and worked my way up to .05 ml in about 3 steps. I also found that taking 100 mg Viagra first was too much. With that much Viagra, .05 ml Trimix is too much for me.

After the experimenting that I did I now have erections that are very close to the non-medicated variety before cancer. On several occasions they have subsided after climax much like the natural erections did.

Like everything else in our fight with this disease, overcoming ED takes lots of patience. We have to take charge of our recovery because the docs have no personal experience in this area. ED treatment is another area where the "one size fits all" approach to medicine just doesn't work.

Jim

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Age 73. Diagnosed 11/03/06. PSA 7.05. Stage T2C Gleason 3+3.

Tamu, you are very observant. True, in my mind I should have only taken 0.12 based on the results I had with 0.08. I remembered what the PA instructed me to do based on what she saw using 0.10 so I reluctantly injected 0.20. I paid the price and she appologized today. In all honesty, she was correct based on what she observed and I didin't put 2 + 2 together. We both learned and maybe on Monday I will cautiously inject 0.06 for starters and move up the scale as required. I hope the pain will not be strong and the body will get somewhat accustomed to the med's as time goes on. If pain persists at the lower levels then I will begin talking about bimix.

I did notice even at 0.08 that manual stimulation enhanced the erection and prolonged it. I need to be cognizant of that. One hour would be thankful and adequate. OD is an ugly feeling.
Geon

Biker90,  I am slowly picking up the experimentation with injection therapy.  My URO has discontinued my Cialis when I started with trimix.  My schedule now is to to injections twice a week (low dose) and high dose(?) for intamicy along with the VED on off days.  They feel that this series should bring my natural erections back sooner.

Hope you right that erections will feel more normal with dose adjustments.  I'll be backing off and starting over on Monday with 0.06 and stay there for a couple of weeks to see how stable the efffects are.  I am sorry that you had a prolonged erection for 5-1/2 hours.  It is painful and supersensitive.  I could not believe the exchange doc suggested manual climax last night as a relief knowing how painful the penis was.  Hope this condition does not happen to either of us as well as to any one else again.  But I'm sure it will by accident.