The Shot!

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kdnole Regular Member Date Joined Jun 2007 Total Posts : 152	Posted 10/11/2007 3:38 PM (GMT -6)
	Well here's one for the books, so Doug get ready to change your pad I go into see my urologist today to get my first Trimix shot for ED, and yes I'm freaking out about having a needle in my penis let alone having a grown man playing with my soon to be erection. So, I get the shot .2cc and off I go with a beautiful bouncing boy, ah what a wonderful sight. Well be careful what you wish for. As the seconds, minutes, hours go by I'm not laughing anymore and it's like someone has put my johnson in a clamp and started to try and get blood out of a turnip. So, hi ho back to Duke I go. As of hour 4 1/2 I am laying on a table getting ready to have 1 small needle and 2 needles that looked to be at least a foot long place into the diamond cutter. Well after the almost painless procedure Mr. Johnson is back to his post PCa surgery size and much happier and so am I. The plus out of today's excersise is - .2cc is not a lot so the Dr. think's I have some "good stuff in there". The next step is to make another appt. with my Dr. to receive another dose of Trimix, but only .1cc. In closing it was nice to see my best friend again even though we had to sedate the crazy ******. Age 44 PSA 4.8 Gleason 3+3=6 T2 Biopsy - 3 of 12 (2@20% / 1@80%) Da Vinci 7/31/07 @ Duke 2.5 hr. surgery, released from Duke with in 14 hrs. Saved both nerve bundles. Foley out 8/10/08 Positive Pathology Report Near left side nerve bundle New Gleason 7 Oncology visit in the near future for radiation Back to work 3 weeks following surgery - Sales 9/13/07 - 1 Post PSA Undetectable less than 0.1 9/17/07 - Pad Free! Back to Top

biker90 Veteran Member Date Joined Nov 2006 Total Posts : 1464	Posted 10/11/2007 4:21 PM (GMT -6)
	Hi kdnole, Sorry you had a painful experience with the Trimix. This is another testimonial that some docs who try to go by the book in our treatment get it wrong. I found that .1 ml was way too much and had to cut it to .02 and work my way up in order to avoid the pain and get the erections to come down in a reasonable time. I don't understand why docs don't start low and work up. Also, not having erections for an extended period then suddenly getting a "diamond cutter" really is a shock to junior down there. He was a lot happier to get hard after a few times using the shots. Good luck... Jim Age 73. Diagnosed 11/03/06. PSA 7.05. Stage T2C Gleason 3+3. RRP 12/7/06. Nerves and nodes okay. Pathological stage: T2C. Gleason 3+4. Cancer confined to prostate. PSAs from 1/3/07 - 7/18/07 0.00. T level on 4/2/07 - 48 On 7/16/07 - 613 Started Tri-Mix on 8/7/07. .02 ml and 50 mg Viagra. It works!!! Next PSA and T tests on 10/17/07 "Patience is essential, attitude is everything." Back to Top

41diagnosed Regular Member Date Joined Jun 2007 Total Posts : 176	Posted 10/11/2007 9:47 PM (GMT -6)
	Well, maybe if it was bigger the bigger dosage wouldn't have been an issue That'll teach you to boast a big one. hehe Seriously, these things can be scary when they don't go according to plan. I'll heed the story and encourage my doc to start out slowly. Dr. Catalona recommends starting on injections 6-8 weeks post surgery and feels the blood flow is helpful to the ED rehab. 42 yo. PSA 4.65 Gleason scores from 4 pathologies of the same biopsy with 2 of 12 cores positive for cancer (if this isn't confusing to the patient...): 1) both cores 3+4 (Weiss Memorial) 2) one 3+4 and one 3+3 (Univ. of Chicago Hosp.) 3) both cores 3+3 (Mass General Hosp.) 4) both cores 3+4 (Northwestern Memorial Hosp.) 9/17/07 - Radical Retropubic Prostatectomy Surgery at Northwestern Memorial in Chicago by Dr. William Catalona. and the winner is...post op Gleason score of 3+4. Good pathology report with negative margins, no seminal vesicale involvement, no lymphatic or vascular invasion, bladder and urethral free and tumor volume was 5% of 27.3g. Amazing how something so small can cause such problems! 9/27/07 - Catheter removal...let the games begin... Back to Top

kdnole Regular Member Date Joined Jun 2007 Total Posts : 152	Posted 10/12/2007 7:30 AM (GMT -6)
	Thanks 41, maybe I'll go down to .01cc :-p Age 44 PSA 4.8 Gleason 3+3=6 T2 Biopsy - 3 of 12 (2@20% / 1@80%) Da Vinci 7/31/07 @ Duke 2.5 hr. surgery, released from Duke with in 14 hrs. Saved both nerve bundles. Foley out 8/10/08 Positive Pathology Report Near left side nerve bundle New Gleason 7 Oncology visit in the near future for radiation Back to work 3 weeks following surgery - Sales 9/13/07 - 1 Post PSA Undetectable less than 0.1 9/17/07 - Pad Free! Back to Top

Tamu Veteran Member Date Joined Oct 2006 Total Posts : 626	Posted 10/12/2007 8:31 AM (GMT -6)
	The .20 cc's is a lot for a starter. Good greif, you would think that a urologist would know better. Now that you have survived several inkections in a short period of time the ones in the future should not be very tough. As already mentioned after not having any erections for a while those first few do cause a little discomfort. Tamu Diagnosed 7/6/06, 1 of 10 core samples, 40%,Stage T1c, Gleason 3+3 Da Vinci on 11/01/06, Catheter out on 11/13/06 56 Years Old Post Op Path, Gleason 3+3, Approx. 5% of prostate involved Prostate Confined, margins clear Undetectable PSA on 12/18/06 No more pads as of 1/13/07 Began injections in April '07 Undetectable PSA on 6/25/07 Back to Top

kdnole Regular Member Date Joined Jun 2007 Total Posts : 152	Posted 10/12/2007 11:27 AM (GMT -6)
	I agree that it was painful but, it was a beautiful day for at least an hour. Next time he wants to cut that dosage to .1cc., I'm thinking .05cc. No comments 41. Age 44 PSA 4.8 Gleason 3+3=6 T2 Biopsy - 3 of 12 (2@20% / 1@80%) Da Vinci 7/31/07 @ Duke 2.5 hr. surgery, released from Duke with in 14 hrs. Saved both nerve bundles. Foley out 8/10/08 Positive Pathology Report Near left side nerve bundle New Gleason 7 Oncology visit in the near future for radiation Back to work 3 weeks following surgery - Sales 9/13/07 - 1 Post PSA Undetectable less than 0.1 9/17/07 - Pad Free! Back to Top

Pete42 Regular Member Date Joined Mar 2007 Total Posts : 114	Posted 10/12/2007 5:21 PM (GMT -6)
	Kdnole- Know exactly what you mean about seeing the guy standing up for the first time in a while, makes you feel like shouting out to the world "Look what I got!" I just started the tri-mix, did my first injection by myself .05, good result, alittle aching but I agree with those who say its probably because the little guy has been resting for so long. My doc recommends 3 times week. Diagnosed 1/26/07 Stage Tc1 Gleason 6 PSA 3.8 12 samples, positive in one 15% Biopsy - 1% involvement, no bladder neck, Gleason 3+3, Tc1 Age 51 Surgery (robotic) May 4 2007 City of Hope Final pathology - fully contained to prostate, TC1, Gleason 3+ 3 Fully continent one month First Post op PSA - Undetectable Second Post Op PSA (8/22/07)- Undetectable Still no luck with ED start injections 10/06/07 Back to Top

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