Post-surgical PSA tests - "standard" or "ultra-sensitive

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

Regular Member

Date Joined Aug 2007
Total Posts : 118
   Posted 10/14/2007 8:11 PM (GMT -6)   
I have robotic surgery with Dr. Patel this Friday. Thinking ahead to the follow-up PSA tests, should I go for the "ultra-sensitive" kind? On one hand, I've heard that it can give an earlier indication of recurrence. On the other hand, I would think that "PSA anxiety" would be an issue.  One urologist had told me that there is no statistical benefit for adjuvant therapy until/when/if a PSA reaches 0.4 or above. Would post-surgical pathology have any bearing to the choice? Thanks

Diagnosed 08/21/07 with T1c cancer
1 of 12 biopsy cores positive; 10% tissue
Gleason score: 3+3=6
PSA level prior to biopsy: 4.3 (velocity < 0.4ng/ml)
Prior biopsy 3 years ago was negative
Prostate is ~24g

Regular Member

Date Joined Feb 2007
Total Posts : 400
   Posted 10/14/2007 8:50 PM (GMT -6)   


First, wishing you the best on your upcoming surgery.  My feeling is, unless your path report from surgery indicates some problem, you should concentrate on healing from the surgery and not dwell on the future PSA right now.  I did not have surgery, but thought that 0.2 was considered a possible recurrence.  Again, good luck.


Tony Crispino
Veteran Member

Date Joined Dec 2006
Total Posts : 8128
   Posted 10/14/2007 8:56 PM (GMT -6)   
Good question, CaPCA,
You look in good shape for excellent results after surgery. But my oncologist does not feel inclined to give me ultra sensative tests, and I had a bad post-op pathology. He does not agree, however, with the 0.4 thing. He and my radiation oncologist were split on radiations benefit, but He absolutely felt that I needed hormone treatment right away and while I have never had a post-op PSA indicate any rise in PSA. In fact my RO was able to show studies that indicated that people who have my stage were benefitting from post-op HT and RT when it was done before a rise in PSA. While noone is home free when they were positive for PCA, your diligence to keep on it may have just been the best medicine for you. Good luck in your surgery.

Age 45 (44 when Dx)
Pre-op PSA was 19.8
Surgery on Feb 16, 2007
Post-Op Pathology was poor: Gleason 4+3=7, 4 positive margins, Stage pT3b (Stage III)
HT began in May, '07 with Lupron and Casodex 50mg
IMRT radiation for 38 Treatments ending August 3, '07
My PSA did drop out after surgery to undetectable.  It has not returned and I will continue HT until January '08.
My Life is supported very well by family and friends like you all.

Veteran Member

Date Joined Apr 2006
Total Posts : 1732
   Posted 10/14/2007 9:26 PM (GMT -6)   
First 2 post-op PSA's should be an ultrasensitive test IMHO. After that it's dealers choice. The accepted practice is at least one ultrasensitive 3 months post-op. Good Luck To Ya!


Veteran Member

Date Joined May 2006
Total Posts : 2542
   Posted 10/18/2007 3:13 PM (GMT -6)   

   tongue   Hi ~  CaPCA & Loved Ones,


Thinking of you and sending special thoughts your way as you move toward surgery day…  As you feel up to it ~ touch base!!


We hope  “Our Journey” helps to guide you over at least one stepping-stone on your path.  Keeping you close… in thoughts and prayers. 


“Our hands will be on your shoulders”

special words borrowed from hamala


In Friendship,


~~*~~*~~*~~~)*&^%  Group Hug %^&*(~~~*~~*~~*~~


From the 3 of us...

Lee, Buddy, & Murphy



Threads started by:  CaPCA

New to Forum - need some advice on nerve bundle sparing

Post-surgical PSA tests - "standard" or "ultra-sensitive

"Enhancements" to the nerve-sparing prostatectomy


mama bluebird - Lee & Buddy… from North Carolina


v          We invite you to visit our personal thread:  Click Here:  “Our Journey” ~ Sharing is Caring 

April 3, 2006  53 on surgery day

RRP / Radical Retropubic Prostatectomy

PSA 4.6   Gleason  3+3=6    T2a   Confined to Prostate

3rd PSA 08-07-2007 Less than 0.1 Non-Detectable :)

Regular Member

Date Joined Aug 2007
Total Posts : 120
   Posted 10/18/2007 5:09 PM (GMT -6)   
Can someone tell me what is a standard and ultra sensitive PSA test? Uncle Dan
Age 67
No symptoms, DRE negative
10 - 06 PSA 5.44, 01 - 07 PSA 6.47
5 - 07 CT and Bone scans negative
05 - 07 Biopsies, 2 of 6 positive
Gleason Score (3+4) 7 Stage T1c
08 - 14 Dr. Dasari - Baptist Hospital, Nashville
da Vinci RAP, five hours surgery
Some right nerve and all left nerve removed,
Hospital discharged 8 - 16
Pathology report Negative margins
Encapsulated, 50% left side
Lymph nodes 2 R & 1 L - Negative
R & L seminal vesicles - Negative
Gleason changed (4+3) 7 closer to 8 than 6
9 - 26 Great PSA 0.000
9 - 27 Starting on meds for ED
9 - 30 Dry, 2nd day without pad
Viagra no help yet

New Topic Post Reply Printable Version
Forum Information
Currently it is Monday, September 24, 2018 8:38 PM (GMT -6)
There are a total of 3,006,276 posts in 329,320 threads.
View Active Threads

Who's Online
This forum has 161825 registered members. Please welcome our newest member, TheRayf.
290 Guest(s), 9 Registered Member(s) are currently online.  Details
Froggy88, cjgk, Ides, Admin, Dewayne, Healing98, Ultimo_G, Y o g i, Worried Guy