radiation therapy after RP

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maldugs
Veteran Member


Date Joined Jun 2007
Total Posts : 782
   Posted 11/2/2007 5:41 PM (GMT -7)   
Hi everyone, is there anyone who has had radiation therapy after RP in circumstances similar to mine? (see latest PSA) and if so, what was the outcome? would appreciate any feedback.
 
Regards Mal.
age 67 PSA 5.8 DRE slightly firm Rt
Biopsy 2nd July 07 5 out of 12 positive
Gleason 3+4=7  right side tumour adenocarcinoma stage T2a
RP on 30th July,
Post op Pathology, tumour stage T3a 4+3=7, microcsopic evidence of capsular penetration, seminal vessels, bladder neck, free of tumour, lymph nodes clear, no evidence of metastatic malignancy, tumour does not extend to the apical margins.
Post op PSA 0.5 26th Sept. next PSA 26th Oct. seeing Radiation Onocologist 31st Oct. PSA 0.5 23rd October.


Doting Daughter
Veteran Member


Date Joined Aug 2007
Total Posts : 1064
   Posted 11/2/2007 6:02 PM (GMT -7)   

Hi Mal! My father is in a similiar siutation, however, he has not started HT or radiation yet.  His first post op PSA came back two weeks ago as .07 and both his surgeon and a radiation oncologist recommend doing RT and HT....my father's situation is different than yours in that he had a positive node, therefore, they would have recommended RT and HT most likely regardless of what the PSA was. 

He is set to start HT in a couple of weeks and hopefully RT once his incontinence improves.  LasVegas Tony has been an incredible resource on RT and if you look through some of the previous posts, you can get even more info on other members who have done RT. 

Best of luck with your decision process! We know how hard it is! 

Doting


Father's Information
DX July 15, 2007
Age 62 (now 63)
PSA 5.5
Original Gleason 3+4=7 
Post Surgery Gleason- 4+3=7
DaVinci Surgery Aug 31, 2007
Positive Right Margin
One positive node
Bone Scan/CT Negative (Sept. 10, 2007)
T3a N1 M0
In process of determining follow up therapy
 
 


hawkfan75
Regular Member


Date Joined Jan 2007
Total Posts : 165
   Posted 11/3/2007 7:30 PM (GMT -7)   
I'm fairly similar to your circumstances.   Since I had positive margins, my doctors pointed out that two recent studies show that HT and RT within the first year will decrease the probability of reoccurance.  When I reached .08, I agreed to the treatment.  I had two months of Zoladex prior to 32 radiation treatments, finishing October 8.  Fortunately, I really didn't have any side effects from the radiation, and minimal ones from the hormones.  I get my first post radiation PSA in December, when I see my surgeon and get another Zoladex injection.  I have to admit that I'm anxious about how things are going, but confident that the radiation caught any loose PC cells that happened to be left behind.

PSA 4.7 (up from 3.2 one year ago)
Biopsy November 8, 2006 1 of 10 cores positive 5% LEFT Side Gleason 3+3
Robotic surgery January 19, 2007
Post Surgery Pathology
     Stage T3a, Gleason 3+4, positive margins and
     capsular penetration RIGHT Side
Post Surgery PSA:  March 5:  0.01
5 month PSA, June 13, 2007:  0.08
Adjuvant therapy began June 26 with Zoladex injection
Radiation began August 23
 


sterd82
Regular Member


Date Joined Sep 2006
Total Posts : 187
   Posted 11/3/2007 7:50 PM (GMT -7)   

Maldugs,

I'm pretty similar to you in stage and Gleason (my signature below gives my stats).  I had IMRT that ended Feb 1... they also put me on hormone therapy for six months (although it was supposed to wear off five months ago, I still feel the side effects).

As far as outcome, my PSA dropped from .24 post surgery to undectable, but the hormone therapy would do that.   The next several years will tell the real story.   The best I can estimate from the information I've looked at is that there's about a 50% chance of recurrence, more or less, at where I sit right now.   So the glass is either half full or half empty... I prefer to look at the half full side of the equation and assumed I'm cured until its shown otherwise.

My next PSA is at the end of this month... judging by my hot flashes and lack of libido, I'm thinking my testosterone is still shut down--- I really don't think I'll have a change in PSA this time around --- they'll check it six months later.  The way I see it, if I can make it to the five year mark, I start seeing some light at the end of the tunnel, even though PC can recur further out than that.

If I do get a PSA recurrence, I assume I'll go back on hormone therapy, which can keep the disease at bay for many years in some cases.  At that point, I'd go to a leading research facility like University of Michigan and see about clinical trials, etc.  My goal would be to buy as much time as possible... sooner or later this is going to be cured, right?   Hopefully, I'm cured already from the radiation/hormone combination.

Not sure if this is the type of information you're lloking for, Maldugs ---- hope this helps - fire back any questions.


Sterd82
Age 47
Open Radical Prostatectomy 6/9/2006
Pathological Stage T3a, Positive Surgical Margin
Gleason 3+4
PSA rose to .24 in November of 2006
6 month hormone therapy initiated December 1. 2006
36 sessions of IMRT Ended Feb 1, 2007
PSA as of May 25, 2007 undetectable
Next PSA November, 2007


Tony Crispino
Veteran Member


Date Joined Dec 2006
Total Posts : 8122
   Posted 11/4/2007 6:53 AM (GMT -7)   
Hi Malgugs,
You can read my signature and see we are nearly the same, my exception is the seminals being involved and the grossly abnormal PSA. But I have fared well since surgery, HT, RT, and believe you will do just as well. I believe Sterd's assessment is about where I am. I never had a PSA climb after surgery but it was likely to happen when I decided to dam the torpedoes and fire away at it. If you have any questions I am sure that the posters will be quick to respond. Sorry you are part of this exclusive club, but in hoping you will get through it without issue, you have our thoughts and prayers.

Tony
Age 45 (44 when Dx)
Pre-op PSA was 19.8
Surgery on Feb 16, 2007
Post-Op Pathology was poor: Gleason 4+3=7, 4 positive margins, Stage pT3b (Stage III)
HT began in May, '07 with Lupron and Casodex 50mg
IMRT radiation for 38 Treatments ending August 3, '07
 
My PSA did drop out after surgery to undetectable.  It has not returned and I will continue HT until January '08.
 
My Life is supported very well by family and friends like you all.
 
STAY POSITIVE!


maldugs
Veteran Member


Date Joined Jun 2007
Total Posts : 782
   Posted 11/5/2007 4:32 PM (GMT -7)   
Thanks to you all for the thoughts and advice, just recieved a call from Onocologist office, and have an appointment next Tuesday for preparation for radiation, will know then when the treatment will start, I feel very well, and positive about the outcome, in the meantime leading life normally (except total ED) but that is a minor problem to me right now.

age 67 PSA 5.8 DRE slightly firm Rt
Biopsy 2nd July 07 5 out of 12 positive
Gleason 3+4=7  right side tumour adenocarcinoma stage T2a
RP on 30th July,
Post op Pathology, tumour stage T3a 4+3=7, microcsopic evidence of capsular penetration, seminal vessels, bladder neck, free of tumour, lymph nodes clear, no evidence of metastatic malignancy, tumour does not extend to the apical margins.
Post op PSA 0.5 26th Sept. next PSA 26th Oct. seeing Radiation Onocologist 31st Oct. PSA 0.5 23rd October.


sterd82
Regular Member


Date Joined Sep 2006
Total Posts : 187
   Posted 11/5/2007 6:21 PM (GMT -7)   
GOOD LUCK, MALDUGS... we're all in your corner here!

Sterd82
Age 47
Open Radical Prostatectomy 6/9/2006
Pathological Stage T3a, Positive Surgical Margin
Gleason 3+4
PSA rose to .24 in November of 2006
6 month hormone therapy initiated December 1. 2006
36 sessions of IMRT Ended Feb 1, 2007
PSA as of May 25, 2007 undetectable
Next PSA November, 2007


jwb187
Regular Member


Date Joined Apr 2007
Total Posts : 101
   Posted 11/6/2007 4:58 AM (GMT -7)   
Hi Mal,

My pc is very similar to yours, in fact probably a little more advanced and aggressive. I just finished IMRT with the Novalis Shaped beam system, uses 9 different angles to shoot you from. I had absolutely no side effects with this system. I also am taking HT therapy (Lupron) started in June before I started my RT in September. I am scheduled to take the HT for two years as my Doc's said this was the normal protocol for someone with my stage of the disease. My initial psa six weeks after davinci was .62 down from 4.57 before. After 3mo's of HT it had dropped to .08. I hope that my next psa which I get in December will be below that. My doc says that anything below .05 is considered undectable. Good luck in you search for successful treatment. JWB
age: 61
PSA 4.57 - Positive DRE
Biopsy 3-19-07 - Gleason 4+4=8
Negative bone scan 3-20-07
DaVinci 4-24-07
Catheter out 5-01-07
post op pathology:
positive margin left side of prostate
left seminal vesicle involved (both removed)
No lymph node involvement
New gleason score 9
T3B....radiation consult on 5-9-07.
June 5, 2007 1st psa post surgery 0.62
June 27, 2007 second psa post surgery 0.59
June 27, 2007 started Lupron injection (24 mos)
September 6, 2007 scheduled to be marked and prepped for radiation therapy.
Start IMRT therapy on September 13, 2007.
September 26,2007 psa test .08
Finished IMRT therapy October 31!!!


M. Kat
Veteran Member


Date Joined Jul 2006
Total Posts : 715
   Posted 11/6/2007 5:17 AM (GMT -7)   
hey guys, I just wanted to say that I'm proud to be associated with such fighters and positive thinkers. You are continuing to fight the good fight and I'm praying that all of you will see those lower PSA numbers!! God bless, kat
Husband Jeff 56 years old diagnosed July 27, 2006
PSA 6.5, 2 positive areas in biopsy, Gleason 3+3=6
Radical Retropubic Prostatectomy August 30, 2006
pathology report - all clear - cancer gone
1st post-surgery PSA test <0.1, 2nd post-surgery PSA test <0.1, 3rd PSA <0.1
no more pads Oct 12, 2006
first "real" erection with use of pump 12/16/06
3/07 - occasional dribbles and erections with Cialis and pump
8/07 - 1 yr PSA <0.1
9/1/07 - achieved erection with Viagra - no pump!

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