PSA Doubling Time Question?

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anniea
Regular Member


Date Joined May 2007
Total Posts : 234
   Posted 11/4/2007 5:49 PM (GMT -7)   
Hi Everyone!!!
Hope you are all doing well. I have a question that maybe you can clarify for me. I did a Prostate Nomogram and this worries me I listed the following:
 
04/29/2007  0.02
06/09/2007  0.02
07/06/2007  0.03
09/26/2007  0.07
11/01/2007  0.1
 
The caculation says Slope Log (PSA) months      0.29
Doubling Time                                                2.42 months
Velocity                                                        0.01  ng/mL/mo
 
Can anyone please explain what all this means. I have read that a doubling time of less than a year is bad, how bad is it and did I enter the numbers right.
 
Thanks for your help
Diana  
Rick & Diana
6-30-06  PSA 2.54
1-22-07  PSA 4.98
1-26-07  PSA 5.09
Diag: 2-14-07 Gleason 8 Stage T1c PSA 5.09
Bone Scan 3-1-07 Clear
3-6-07 Triple Spinal Fusion (due to old back injury)
Radical retropubic surgery 4-2-07  Post surgery Gleason 9 Stage T3a Positive margins
4-29-07 PSA 0.02
6-9-07   PSA 0.02
7-6-07   PSA 0.03
8-1-07   CT Scan & Chest X-Ray   Clean
 9-26-2007 PSA 0.07
11/1/07 PSA 0.1


Tony Crispino
Veteran Member


Date Joined Dec 2006
Total Posts : 8122
   Posted 11/4/2007 7:38 PM (GMT -7)   
I think you entered them correctly but that I see varying things that don't put as much emphasis when the values are .1 or less. But I have read that after surgery the median doubling rate after recurrance was .8 years for mortality on patients who died within 5 years. Without treatment it can be an issue and you kids know my thoughts about it. HT will likely drop his PSA to undetectable for many years. I know Rick wants to avoid it. But maybe he sould at least consider Casodex and Proscar. There are really no side effects with it and it too can deliver a PSA stabilizing effect. You guys have our love and thoughts. God Bless you.

Tony
Age 45 (44 when Dx)
Pre-op PSA was 19.8
Surgery on Feb 16, 2007
Post-Op Pathology was poor: Gleason 4+3=7, 4 positive margins, Stage pT3b (Stage III)
HT began in May, '07 with Lupron and Casodex 50mg
IMRT radiation for 38 Treatments ending August 3, '07
 
My PSA did drop out after surgery to undetectable.  It has not returned and I will continue HT until January '08.
 
My Life is supported very well by family and friends like you all.
 
STAY POSITIVE!


anniea
Regular Member


Date Joined May 2007
Total Posts : 234
   Posted 11/4/2007 8:05 PM (GMT -7)   

Hi Tony,

Thanks for your reply. Rick has agreed to see if his cardilogist (sp) would check him out for hormone treatment. I am going to call in the morning for an appointment. I have to take baby steps but I'm trying one at a time. I just hope his heart is in good enough condition to be able to do this.

Thanks again & God Bless you both

Diana


Rick & Diana
6-30-06  PSA 2.54
1-22-07  PSA 4.98
1-26-07  PSA 5.09
Diag: 2-14-07 Gleason 8 Stage T1c PSA 5.09
Bone Scan 3-1-07 Clear
3-6-07 Triple Spinal Fusion (due to old back injury)
Radical retropubic surgery 4-2-07  Post surgery Gleason 9 Stage T3a Positive margins
4-29-07 PSA 0.02
6-9-07   PSA 0.02
7-6-07   PSA 0.03
8-1-07   CT Scan & Chest X-Ray   Clean
 9-26-2007 PSA 0.07
11/1/07 PSA 0.1


Tony Crispino
Veteran Member


Date Joined Dec 2006
Total Posts : 8122
   Posted 11/4/2007 9:52 PM (GMT -7)   
Wow Diana,
What a great message. Now my prayers are intensified. I pray that the cardiologist can find a way with your oncologist to balance the scales give Rick a great shot at it. His PSA is still very low and he could even be told to wait until it hits a point that ht can be more effective. I hear that .4 is the usual magic number. But I have read where patients a 3000 was zeroed out and doing quite well. But thank you for this message. So baby steps it is...

:-)

Tony
Age 45 (44 when Dx)
Pre-op PSA was 19.8
Surgery on Feb 16, 2007
Post-Op Pathology was poor: Gleason 4+3=7, 4 positive margins, Stage pT3b (Stage III)
HT began in May, '07 with Lupron and Casodex 50mg
IMRT radiation for 38 Treatments ending August 3, '07
 
My PSA did drop out after surgery to undetectable.  It has not returned and I will continue HT until January '08.
 
My Life is supported very well by family and friends like you all.
 
STAY POSITIVE!

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