open prostate surgery, IMRT, Brachytherapy, Davinci---gentlemen a poll is in order please give your pathology situation and what guided your decisions. I was diagonosed 0ct 2007,having had a psa rise from 2.9 to 4.7 in 12 months,---had T1c, gleason 3+3=6 and 66cc size. Since I was on testosterone replacement, they immediately sugested I stop replacement. After much research I find that it is inconclusive whether testosterone deprivation is necessary, but that it is possible that estrogen deprivation, and increasing progesterone would work better. I have even found out that the PSA is also important in that it is the body's method to attack the cancer in the prostate--it appear to be anti-angiogenesis.Their are many studiesout there with many condridicting each other.---How then do you make a clearn decision.