Tofranil

 Tofranil has a side effect of urinary retention....hope it helps :>)

 

 

Post edited: Subject showing No Subject....added Title

* bluebird ~ Moderator for Prostate Cancer Forum

Post Edited By Moderator (bluebird) : 11/28/2007 11:31:59 AM (GMT-7)

    Swimmom,  Do you know why or how it does it.  Do you think it would be something I should ask my Dr about?

    Willing to try anything at this point!

    KW

KW,

I'd have to look in the PDF to remember but I know its been used in the past for treating bed wetting in children.
A history of difficulty urinating is one of its contraindications. I'll try to look it up to refresh my memory.

Swim

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According to what I read: "Mayo Clinic" Tofranil causes the bladder muscle to relax while causing the smooth muscles at the bladder neck to contract.

Another site reported that it causes increased muscle tone in the bladder neck. It is an antidepressant which has also been used to help with bed wetting in children.

Julie

Not sure how this ended up a seperate post from my reply but BLUE-----BIRD...can you fix it? :>)

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Just thought I would update everyone on the Tofranil medication that my dad started. It's been about 5 months that he's been on it and his incontinence is still about zero.

I just talked to him a little bit ago and he was going to start weaning himself off of it and see if there was any difference. He had surgery last August and started Tofranil in Dec or Jan...I really can't recall. He had pretty significant incontinence up until that point, and the week he started the drug there was an amazing difference. So was it due to natural recovery or medication, we really won't know. But whatever it was it worked.

Julie

Any big side effects?

I have kidney disease, so wondering if I would be a candidate?

He hasn't noticed any side effects....I think it says the usual...dry mouth etc..and I don't really know about contraindications??

He was just happy that "something" helped the incontinence. He had an appointment scheduled at an incontinence clinic and really felt like he didn't need to go by the
time the appointment came around. He did keep the appointment though.

Julie

Swim-

You've been on the 'puter too much. PDR, not PDF.

-Les

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1/2005 Dx PSA 26.5 Gleason 7 (4+3) @Age 61
1/2005 Start Casodex and Zoladex
PSA drops to <0.01
7/2005-8/2005 5 weeks of IMRT and then HDR brachy
1/2007 Rad Oncologist orders CT scan of pelvis
because of complaints of pain in both thighs
MRI confirms pain not caused by cancer BUT
1/2007 CT scan of pelvis picks up a nodule at bottom of left lung
5/2007 CT scan of lungs shows 1/2007 nodule has grown and
there are numerous nodules on both lungs.
6/2007 Thoracic surgeon removes wedge of left lung for biopsy
6/2007 Path report says 95% chance of metastatic PCa, but she's
never seen cells like this before.
8/2007 2nd opinion at M.D. Anderson in Houston.
They confirm: mutated PCa, very rare, but seen there 2 or
3 times. Recommendation: have CT scans every 6 weeks
and watch for change. At that point start chemo and will
survive for 22 - 24 months thereafter.
PSA still undetectable, but get Lupron shot to bring T down from 27
2/2008 Trip to Houston – PSA now 0.5 and nodules larger. Lupron shot.

LOL...funny, I never noticed the typo...Physician's Desk Ref...thanks for the edit :>)

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