PSA Update & Question

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anniea
Regular Member


Date Joined May 2007
Total Posts : 234
   Posted 12/3/2007 11:58 PM (GMT -7)   
Hi Everyone,
I hope you are all well and had a good Thanksgiving.
Rick went for his latest PSA and it came in at 0.12, I went to the MSKCC.org web site and entered the information for PSADT & it came back with a doubling time of 2.45 months. My question is: Is his PSA still low? How concerned should I be with a doubling time of 2.45 months? Did I do the entry right? How valid is "Don't worry about PSA until it hits 2". I looked at Mama Bluebirds definition and understand that he is at 12 pennies if I read it correctly. Did I? If Rick continues to do nothing will the PSA start to rise faster as the cancer grows? Last question: If Rick stays on statin drugs which I have been told keep the PSA reading low, How will we really know what the PSA is doing?
Thank you in advance for your help. I am sorry to have so many questions but I really don't know what to expect.
Thanks Diana
Rick & Diana
6-30-06  PSA 2.54
1-22-07  PSA 4.98
1-26-07  PSA 5.09
Diag: 2-14-07 Gleason 8 Stage T1c PSA 5.09
Bone Scan 3-1-07 Clear
3-6-07 Triple Spinal Fusion (due to old back injury)
Radical retropubic surgery 4-2-07  Post surgery Gleason 9 Stage T3a Positive margins
4-29-07 PSA 0.02
6-9-07   PSA 0.02
7-6-07   PSA 0.03
8-1-07   CT Scan & Chest X-Ray   Clean
 9-26-2007 PSA 0.07
11/1/07 PSA 0.1


Tony Crispino
Veteran Member


Date Joined Dec 2006
Total Posts : 8122
   Posted 12/4/2007 12:28 AM (GMT -7)   
Hi Diana,
I very much thought about you and Rick this T-day. I do not fully understand this questions answers. Many doubling rates are slowed by relatively simple non-side effect methods. And the high PSA's can hang around for a while. But his PSA is not high as yet and you both can be thankful. That makes it a better T-day than most!

Tony
Age 45 (44 when Dx)
Pre-op PSA was 19.8
Surgery on Feb 16, 2007
Post-Op Pathology was poor: Gleason 4+3=7, 4 positive margins, Stage pT3b (Stage III)
HT began in May, '07 with Lupron and Casodex 50mg
IMRT radiation for 38 Treatments ending August 3, '07
 
My PSA did drop out after surgery to undetectable.  It has not returned and I will continue HT until January '08.
 
My Life is supported very well by family and friends like you all.
 
STAY POSITIVE!


sterd82
Regular Member


Date Joined Sep 2006
Total Posts : 187
   Posted 12/4/2007 4:03 PM (GMT -7)   
Diana,

As just a fellow patient, I'm sure no expert, but Rick's experience sounds familiar, and I really agonized over the PSA question you have, so here's what I found out:

First of all, Rick's PSA dropped very low after surgury, which is great news! THat would tend to make you think that IF there is any cancer left behind, there wan't much. With Geason 9 and positive margins, and I THINK Rick is pretty young if I remember from earlier posts, there's a good chance that there might be some cancer left behind---BUT AGAIN, the good neews that, with a positive margin, its incresed the liklihood that the cancer is still localized.

With a PSA at .12, up from .07, its still low... my doctor said at these low levels PSA doubling time might not mean very much, so don't worry about it.

As far as what level the PSA hits to consider additional treatment, .2 (that's 20 pennies)was the best answer I found NOT 2....DO NOT WAIT THAT LONG.

Localized residual disease is still curable with radiation therapy, but it is most effective if undertaken BEFORE PSA hits .5 (50 pennies). Even without a PSA rise, with a higher Gleason and a positive margin, I think a lot of docs would want to do radiation/hormone combined (Tony and I have both done that, and agree its not all that bad!)

My advice would be to make an appointment with a good radiation oncologist for a consultation, just to see at what level they might treat Rick... and to get the preliminaries out of the way so you're ready in case you get another bump.

God blees and Good Luck ---- I may not be right on this stuff, but its what I followed andf have no regrets!
Sterd82
Age 47 - pre-surgury PSA 39
Open Radical Prostatectomy 6/9/2006
Pathological Stage T3a, Positive Surgical Margin
Gleason 3+4
PSA rose to .24 in November of 2006
6 month hormone therapy initiated December 1. 2006
36 sessions of IMRT Ended Feb 1, 2007
PSA as of May 25, 2007 undetectable
PSA as of November 29, 2007 undetectable
Next PSA May of 2008


anniea
Regular Member


Date Joined May 2007
Total Posts : 234
   Posted 12/5/2007 12:37 AM (GMT -7)   

Hi Tony & Sterd82

Thank You for your responses. It seems Ricks Primary Doc is pretty concerned about him being anemic,(sp) more so than the PSA. I guess we will have to wait and see what the next appointment on the 12th brings???

Warm wishes

Diana


Rick & Diana
Age 68/ 67@ Dx
6-30-06  PSA 2.54
1-22-07  PSA 4.98
1-26-07  PSA 5.09
Diag: 2-14-07 Gleason 8 Stage T1c PSA 5.09
Bone Scan 3-1-07 Clear
3-6-07 Triple Spinal Fusion (due to old back injury)
Radical retropubic surgery 4-2-07  Post surgery Gleason 9 Stage T3a Positive margins
4-29-07 PSA 0.02
6-9-07   PSA 0.02
7-6-07   PSA 0.03
8-1-07   CT Scan & Chest X-Ray   Clean
 9-26-2007 PSA 0.07
11/1/07 PSA 0.1
11/30/07 PSA 0.12

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