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Celiac without HLA genes

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Celiac Disease
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christianfox
New Member
Joined : May 2013
Posts : 1
Posted 5/9/2013 3:11 AM (GMT -6)
A friend of mine got diagnosed with Collagenous Colits about 5 years ago. Also diagnosed with soy allergy at the Enterolab about the same time.
He recently did an HLA and it was negative.
He also did Endomysial Antibody IgA, Gliadin Peptide IgG, Gliadin Peptide IgA and Tissue Transglutaminase IgA - all negative.

Are there any other blood tests?

I read on the Celiac Center page from the Chicago University (http://www.cureceliacdisease.org/archives/faq/can-you-have-celiac-disease-without-having-the-genes-for-it) that Dr Guandalini says that you can't have Celiac without the gene.

According to him if you don’t have the genetic markets for celiac that you don’t have it, and there’s never been any documented cases of anybody having celiac without the genetic markers.

Does anybody know somebody with Celiac who doesn't have this HLA gene? Or can you have something that has the same symptoms as Celiac, but doesn't have the gene - what would it be called and how would you test for it?

Thank you
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Razzle
Veteran Member
Joined : Aug 2007
Posts : 4415
Posted 5/12/2013 10:23 PM (GMT -6)
Can do www.Enterolab.com testing - stool and saliva test looks for genes and stool antibody levels. Can diagnose Gluten Sensitivity as well as Celiac...

Also, I've read that about 5% of biopsy-proven Celiacs don't have DQ2 or DQ8 "Celiac" genes...
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