I haven't experienced what you are going through, but I have been thinking about
I have a few thoughts.
First, are you taking any other thyroid "nutrients," such as selenium, iodine, kelp, L-tyrosine, etc?
Those could contribute to the hyper symptoms because they stimulate the thyroid.
As far as dosage, I have seen several references to incremental dosing of thyroid medication.
I don't know too many doctors who follow this and in fact I hadn't hear of it until I really started
researching Hashimoto's, trying to find some relief for myself.
My favorite book at the moment is Hope for Hashimoto's by Alexander Haskell. He also has
a set of videos at his web site http://hopeforhashimotos.com/ that are extremely informative and
I think well worth the time to view. Anyway, in his book he discusses phases for treating hashimoto's.
In Phase 1 the focus is getting the TSH below 1.0 and he said a person really needs to be on medication
to do this. However he recommends incremental doses:
"The way to prescribe thyroid hormones for Hashimoto's is to begin very low doses, about
one-third or one-fourth of what is normally prescribed for hypothyroidism. Because of T4's
long half-life (seven days), this daily third or quarter will slowly increase T4 levels in the
He goes on to a lengthy explanation of T3 and T4 and how it all works, but he says to continue
at this low dose for 10 days and then if you are not feeling quite as well and feel sluggish, etc.,
increase the dose by another third or quarter. You keep doing this every 10 to 14 days until
you feel balanced. He said if you go over your optimal dose and experience a more rapid heart
rate and feel a little hyper, adjust down by a third or a quarter.
So I don't know what you are taking now, but I would almost be tempted to stop for a few days
for the high T4 dose to clear, then start back at a really low dose and see how that works for you.
I think you were on way too high of a dose to start.
Another thing to consider is adding a little T3 with the T4. That helps a lot of people. Some
people swear by the natural thyroid such as Armour which you can read more about at
Or you can get a prescription for a compounded T4/T3 synthetic medication if your doctor
will go along with that.
The one thing I know for sure is that everyone responds differently to thyroid meds and it might
take a while to find the right combination for you. I've been working on it for two years and I'm
not there yet. If you have any questions, I would be happy to try to help.