Is it Hashimoto's or Graves?

Jenn1202

New Member

Joined : Feb 2014

Posts : 13

Posted 3/15/2014 11:57 PM (GMT -8)

I have a history of low TSH and borderline-high free T4 (meaning HYPER-THYROID right?). Currently my TSH, free T4, and T3 are normal. However my TPO Ab and Thyroglobulin Ab are high.
TPO Ab: 400 IU/mL (ref. range: 0-34)
Thyroglobulin: 80 IU/mL (ref. range: 0-19)

Due to the above results I've been told that I may have Hashimoto's. From what I understand these antibodies are associated with both Hashimoto's and Graves (https://www.arupconsult.com/Topics/Thyroiditis.html). My doctor never checked my TSI levels, how can they know my abnormal results are not associated with Graves? Is this really Hashimoto's or could this be Graves?

jujub

Elite Member

Joined : Mar 2003

Posts : 10424

Posted 3/16/2014 4:04 AM (GMT -8)

Elevated TPO is present in about 95% of people with Hashi's and about 50-60% of people with Graves. Low TSH and high free T4 are associated with hyperthyroidism, which would be Graves disease.

The caveat is that people with Hashi's can have wide-ranging test results, and sometimes even edge into the hyperthyroid range. If you aren't seeing an endocrinologist, that would be a good idea. Be sure to find one experienced in treating thyroid problems, as some are really only experienced with diabetes.

With elevated TPO and normal hormone levels in the absence of symptoms, many endo's will elect to follow and watch rather than treating. This is because there are other factors that can temporarily affect TPO.

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