Posted 8/8/2016 8:54 AM (GMT -6)
Hi Lotus Indigo,
What was your TSH when diagnosed? 75 mcg per day is a little bit high starting dose, 25-50 mcg per day is the right initial dose, depending on your TSH.
Also with hashi most probably you will need to increase the dose several times, with intervals of three months until you reach the proper dose for you.
Natural Desiccated Thyroid (NDT) is made from powdered pig thyroid glands, all contain the same amount of hormones but with different formulations, this is why each one need to find the brand that is suitable for him.
Also the ratio of T3 to T4 in NDT is much higher than that in humans, some feel well on it but many do not, my best guess is that the huge amount of T3 in the NDT makes you hyper of some sort and this is why you feel depressed.
What brand of Levo you were on? can you try others? like Levoxyl and Tirosint?
Best of luck,